Anti-cancer effects of genistein supplementation and moderate-intensity exercise in high-fat diet-induced breast cancer via regulation of inflammation and adipose tissue metabolism in vivo and in vitro

Anti-cancer effects of genistein supplementation and moderate-intensity exercise in high-fat diet-induced breast cancer via regulation of inflammation and adipose tissue metabolism in vivo and in vitro

Abstract Background Breast cancer represents a significant global health concern and is influenced by a range of environmental factors. Increased fat intake and physical inactivity contribute to elevated body fat levels and are strongly linked to breast cancer incidence. Genistein (GEN), isoflavone...

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Bibliographic Details
Main Authors: Hyeji Kwon, Hyejin Han, Yeonsoo Oh, Yuri Kim, Jung-Hyun Kim
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Breast cancer
Genistein
Exercise
Myokine
Apoptosis
Macrophage
Online Access:https://doi.org/10.1186/s12906-025-04968-x
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