Effects of depression on patients suffering from ankylosing spondylitis: a comparative study

ABSTRACT BACKGROUND: Ankylosing spondylitis (AS) is a sustained inflammatory pathology that manifests as increasing rigidity and a continuous decline in spinal flexibility, leading to increasing lumbar pain during rest. OBJECTIVES: This study primarily aimed to evaluate depression assessments usin...

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Main Authors: Antonio Cortés-Rodríguez, Lisa Alves-Gomes, Marta Losa-Iglesias, Juan Gómez-Salgado, Ricardo Becerro-de-Bengoa-Vallejo, Miguel Ángel Saavedra-García, Daniel López-López, Ana María Jiménez-Cebrián
Format: Article
Language:English
Published: Associação Paulista de Medicina 2025-04-01
Series:São Paulo Medical Journal
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802025000200206&lng=en&tlng=en
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author Antonio Cortés-Rodríguez
Lisa Alves-Gomes
Marta Losa-Iglesias
Juan Gómez-Salgado
Ricardo Becerro-de-Bengoa-Vallejo
Miguel Ángel Saavedra-García
Daniel López-López
Ana María Jiménez-Cebrián
author_facet Antonio Cortés-Rodríguez
Lisa Alves-Gomes
Marta Losa-Iglesias
Juan Gómez-Salgado
Ricardo Becerro-de-Bengoa-Vallejo
Miguel Ángel Saavedra-García
Daniel López-López
Ana María Jiménez-Cebrián
author_sort Antonio Cortés-Rodríguez
collection DOAJ
description ABSTRACT BACKGROUND: Ankylosing spondylitis (AS) is a sustained inflammatory pathology that manifests as increasing rigidity and a continuous decline in spinal flexibility, leading to increasing lumbar pain during rest. OBJECTIVES: This study primarily aimed to evaluate depression assessments using the Beck Depression Inventory (BDI) and delineate depressive symptomatology in patients diagnosed with AS compared to those without this condition. DESIGN AND SETTING: A comparative study was conducted in Medical Centers in Málaga, Spain. METHODS: A cohort of 102 participants, with a mean age of 46,80 ± 10,54 years, was divided into two sets: 51 individuals diagnosed with AS (cases) and another 51 without AS (controls), each harmonized across variables such as body mass index, age, and sex. Demographic variables were systematically gathered from each participant, and the BDI responses were accurately recorded and subsequently analyzed for comparison. RESULTS: Of the total sample, the sex distribution was 29.4% male and 70.6% female. BDI scores were higher for the AS group (19.25 ± 15.5) than for the control group (5.33 ± 7). Notably, there were clear statistical differences (P < 0.01) in the BDI categories, with elevated levels observed in participants with AS. CONCLUSION: Individuals with AS experienced higher levels of depression than those without AS. Furthermore, there were sex differences within the case group, with a higher percentage of women than men at any level of depression. Notably, there was a moderate inverse correlation between the number of years since diagnosis and depression level.
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spelling doaj-art-40e5b2e4e8e642008fedc2ad98e7f4512025-08-20T02:26:02ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-94602025-04-01143210.1590/1516-3180.2024.0177.r1.16102024Effects of depression on patients suffering from ankylosing spondylitis: a comparative studyAntonio Cortés-Rodríguezhttps://orcid.org/0000-0002-4660-5596Lisa Alves-Gomeshttps://orcid.org/0000-0003-2154-3461Marta Losa-Iglesiashttps://orcid.org/0000-0001-7588-2069Juan Gómez-Salgadohttps://orcid.org/0000-0001-9053-7730Ricardo Becerro-de-Bengoa-Vallejohttps://orcid.org/0000-0003-1568-7602Miguel Ángel Saavedra-Garcíahttps://orcid.org/0000-0002-9818-6290Daniel López-Lópezhttps://orcid.org/0000-0001-6248-9188Ana María Jiménez-Cebriánhttps://orcid.org/0000-0002-8634-7114ABSTRACT BACKGROUND: Ankylosing spondylitis (AS) is a sustained inflammatory pathology that manifests as increasing rigidity and a continuous decline in spinal flexibility, leading to increasing lumbar pain during rest. OBJECTIVES: This study primarily aimed to evaluate depression assessments using the Beck Depression Inventory (BDI) and delineate depressive symptomatology in patients diagnosed with AS compared to those without this condition. DESIGN AND SETTING: A comparative study was conducted in Medical Centers in Málaga, Spain. METHODS: A cohort of 102 participants, with a mean age of 46,80 ± 10,54 years, was divided into two sets: 51 individuals diagnosed with AS (cases) and another 51 without AS (controls), each harmonized across variables such as body mass index, age, and sex. Demographic variables were systematically gathered from each participant, and the BDI responses were accurately recorded and subsequently analyzed for comparison. RESULTS: Of the total sample, the sex distribution was 29.4% male and 70.6% female. BDI scores were higher for the AS group (19.25 ± 15.5) than for the control group (5.33 ± 7). Notably, there were clear statistical differences (P < 0.01) in the BDI categories, with elevated levels observed in participants with AS. CONCLUSION: Individuals with AS experienced higher levels of depression than those without AS. Furthermore, there were sex differences within the case group, with a higher percentage of women than men at any level of depression. Notably, there was a moderate inverse correlation between the number of years since diagnosis and depression level.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802025000200206&lng=en&tlng=enComorbiditiesAnxietyBehavioral symptomsBone diseasesBeck depression inventoryPsychological assessmentChronic inflammatory diseases
spellingShingle Antonio Cortés-Rodríguez
Lisa Alves-Gomes
Marta Losa-Iglesias
Juan Gómez-Salgado
Ricardo Becerro-de-Bengoa-Vallejo
Miguel Ángel Saavedra-García
Daniel López-López
Ana María Jiménez-Cebrián
Effects of depression on patients suffering from ankylosing spondylitis: a comparative study
São Paulo Medical Journal
Comorbidities
Anxiety
Behavioral symptoms
Bone diseases
Beck depression inventory
Psychological assessment
Chronic inflammatory diseases
title Effects of depression on patients suffering from ankylosing spondylitis: a comparative study
title_full Effects of depression on patients suffering from ankylosing spondylitis: a comparative study
title_fullStr Effects of depression on patients suffering from ankylosing spondylitis: a comparative study
title_full_unstemmed Effects of depression on patients suffering from ankylosing spondylitis: a comparative study
title_short Effects of depression on patients suffering from ankylosing spondylitis: a comparative study
title_sort effects of depression on patients suffering from ankylosing spondylitis a comparative study
topic Comorbidities
Anxiety
Behavioral symptoms
Bone diseases
Beck depression inventory
Psychological assessment
Chronic inflammatory diseases
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802025000200206&lng=en&tlng=en
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