Reversed role of CD36 deficiency in high-fat diet or methionine/choline-deficient diet-induced hepatic steatosis and steatohepatitis

Reversed role of CD36 deficiency in high-fat diet or methionine/choline-deficient diet-induced hepatic steatosis and steatohepatitis

IntroductionCluster of differentiation 36 (CD36) is highly expressed in the liver of patients with metabolic dysfunction-associated fatty liver disease (MAFLD) or metabolic dysfunction-associated steatohepatitis (MASH). However, the precise role of CD36 in MAFLD/MASH is controversial. In the current...

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Bibliographic Details
Main Authors: Wenya Zhu, Jialing Ma, Tingting Zhang, Mengmeng Zhu, Yajun Duan, Xiaoxiao Yang, Yuanli Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
CD36
MAFLD
MASH
HFD
MCD
lipid metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1522177/full
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