Transient Myeloproliferative Disorder in a Neonate without Down Syndrome—A Rare Case Report and Review of the Literature

Transient myeloproliferative disorder (TMD) is a self-limiting disorder characteristically seen in neonates with Down syndrome with or without somatic mosaicism. Trisomy-21 limited to the hematopoietic lineage alone has been described; awareness of which is very important for appropriate evaluation...

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Main Authors: Devaki Menon Kizhakke Vellatt, Dhaarani Jayaraman, Shwetha Amuthan, Umamaheswari Balakrishnan, Teena Koshy, Arun Kumar Subramanian, Julius Xavier Scott
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd.
Series:Indian Journal of Medical and Paediatric Oncology
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1779677
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author Devaki Menon Kizhakke Vellatt
Dhaarani Jayaraman
Shwetha Amuthan
Umamaheswari Balakrishnan
Teena Koshy
Arun Kumar Subramanian
Julius Xavier Scott
author_facet Devaki Menon Kizhakke Vellatt
Dhaarani Jayaraman
Shwetha Amuthan
Umamaheswari Balakrishnan
Teena Koshy
Arun Kumar Subramanian
Julius Xavier Scott
author_sort Devaki Menon Kizhakke Vellatt
collection DOAJ
description Transient myeloproliferative disorder (TMD) is a self-limiting disorder characteristically seen in neonates with Down syndrome with or without somatic mosaicism. Trisomy-21 limited to the hematopoietic lineage alone has been described; awareness of which is very important for appropriate evaluation and counseling in phenotypically normal children.
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institution Kabale University
issn 0971-5851
0975-2129
language English
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series Indian Journal of Medical and Paediatric Oncology
spelling doaj-art-40deceac63d64accbd963d4eec8242952025-08-20T03:25:29ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-212910.1055/s-0044-1779677Transient Myeloproliferative Disorder in a Neonate without Down Syndrome—A Rare Case Report and Review of the LiteratureDevaki Menon Kizhakke Vellatt0Dhaarani Jayaraman1Shwetha Amuthan2Umamaheswari Balakrishnan3Teena Koshy4Arun Kumar Subramanian5Julius Xavier Scott6Department of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Chennai, Tamil Nadu, IndiaDepartment of Pediatric Hemato-Oncology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Chennai, Tamil Nadu, IndiaDepartment of Pediatrics, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Chennai, Tamil Nadu, IndiaDepartment of Neonatology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Chennai, Tamil Nadu, IndiaDepartment of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Chennai, Tamil Nadu, IndiaDepartment of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Chennai, Tamil Nadu, IndiaDepartment of Pediatric Hemato-Oncology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Chennai, Tamil Nadu, IndiaTransient myeloproliferative disorder (TMD) is a self-limiting disorder characteristically seen in neonates with Down syndrome with or without somatic mosaicism. Trisomy-21 limited to the hematopoietic lineage alone has been described; awareness of which is very important for appropriate evaluation and counseling in phenotypically normal children.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1779677congenital leukemiaDown syndromemosaicismtransient abnormal myelopoiesiscase report
spellingShingle Devaki Menon Kizhakke Vellatt
Dhaarani Jayaraman
Shwetha Amuthan
Umamaheswari Balakrishnan
Teena Koshy
Arun Kumar Subramanian
Julius Xavier Scott
Transient Myeloproliferative Disorder in a Neonate without Down Syndrome—A Rare Case Report and Review of the Literature
Indian Journal of Medical and Paediatric Oncology
congenital leukemia
Down syndrome
mosaicism
transient abnormal myelopoiesis
case report
title Transient Myeloproliferative Disorder in a Neonate without Down Syndrome—A Rare Case Report and Review of the Literature
title_full Transient Myeloproliferative Disorder in a Neonate without Down Syndrome—A Rare Case Report and Review of the Literature
title_fullStr Transient Myeloproliferative Disorder in a Neonate without Down Syndrome—A Rare Case Report and Review of the Literature
title_full_unstemmed Transient Myeloproliferative Disorder in a Neonate without Down Syndrome—A Rare Case Report and Review of the Literature
title_short Transient Myeloproliferative Disorder in a Neonate without Down Syndrome—A Rare Case Report and Review of the Literature
title_sort transient myeloproliferative disorder in a neonate without down syndrome a rare case report and review of the literature
topic congenital leukemia
Down syndrome
mosaicism
transient abnormal myelopoiesis
case report
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1779677
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