Acute myocardial infarction in sub-Saharan Africa: the need for data.

<h4>Background</h4>Trends in the prevalence of acute myocardial infarction in sub-Saharan Africa have not been well described, despite growing recognition of the increasing burden of cardiovascular disease in low- and middle-income countries. The aim of this systematic review was to desc...

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Main Authors: Julian T Hertz, Joseph M Reardon, Clarissa G Rodrigues, Luciano de Andrade, Alexander T Limkakeng, Gerald S Bloomfield, Catherine A Lynch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0096688
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author Julian T Hertz
Joseph M Reardon
Clarissa G Rodrigues
Luciano de Andrade
Alexander T Limkakeng
Gerald S Bloomfield
Catherine A Lynch
author_facet Julian T Hertz
Joseph M Reardon
Clarissa G Rodrigues
Luciano de Andrade
Alexander T Limkakeng
Gerald S Bloomfield
Catherine A Lynch
author_sort Julian T Hertz
collection DOAJ
description <h4>Background</h4>Trends in the prevalence of acute myocardial infarction in sub-Saharan Africa have not been well described, despite growing recognition of the increasing burden of cardiovascular disease in low- and middle-income countries. The aim of this systematic review was to describe the prevalence of acute myocardial infarction in sub-Saharan Africa.<h4>Methods</h4>We searched PubMed, EMBASE, Global Health Archive, CINAHL, and Web of Science, and conducted reference and citation analyses. Inclusion criteria were: observational studies, studies that reported incidence or prevalence of acute myocardial infarction, studies conducted in sub-Saharan Africa, and studies that defined acute myocardial infarction by EKG changes or elevation of cardiac biomarkers. Studies conducted prior to 1992 were excluded. Two independent reviewers analyzed titles and abstracts, full-texts, and references and citations. These reviewers also performed quality assessment and data extraction. Quality assessment was conducted with a validated scale for observational studies.<h4>Findings</h4>Of 2292 records retrieved, seven studies met all inclusion criteria. These studies included a total of 92,378 participants from highly heterogeneous study populations in five different countries. Methodological quality assessment demonstrated scores ranging from 3 to 7 points (on an 8-point scale). Prevalence of acute myocardial infarction ranged from 0.1 to 10.4% among the included studies.<h4>Interpretation</h4>There is insufficient population-based data describing the prevalence of acute myocardial infarction in sub-Saharan Africa. Well-designed registries and surveillance studies that capture the broad and diverse population with acute myocardial infarction in sub-Saharan Africa using common diagnostic criteria are critical in order to guide prevention and treatment strategies.<h4>Registration</h4>Registered in International Prospective Register of Systematic Reviews (PROSPERO) Database #CRD42012003161.
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spelling doaj-art-40dcd565dd574be2b07e15a8dad3797d2025-08-20T02:46:01ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0195e9668810.1371/journal.pone.0096688Acute myocardial infarction in sub-Saharan Africa: the need for data.Julian T HertzJoseph M ReardonClarissa G RodriguesLuciano de AndradeAlexander T LimkakengGerald S BloomfieldCatherine A Lynch<h4>Background</h4>Trends in the prevalence of acute myocardial infarction in sub-Saharan Africa have not been well described, despite growing recognition of the increasing burden of cardiovascular disease in low- and middle-income countries. The aim of this systematic review was to describe the prevalence of acute myocardial infarction in sub-Saharan Africa.<h4>Methods</h4>We searched PubMed, EMBASE, Global Health Archive, CINAHL, and Web of Science, and conducted reference and citation analyses. Inclusion criteria were: observational studies, studies that reported incidence or prevalence of acute myocardial infarction, studies conducted in sub-Saharan Africa, and studies that defined acute myocardial infarction by EKG changes or elevation of cardiac biomarkers. Studies conducted prior to 1992 were excluded. Two independent reviewers analyzed titles and abstracts, full-texts, and references and citations. These reviewers also performed quality assessment and data extraction. Quality assessment was conducted with a validated scale for observational studies.<h4>Findings</h4>Of 2292 records retrieved, seven studies met all inclusion criteria. These studies included a total of 92,378 participants from highly heterogeneous study populations in five different countries. Methodological quality assessment demonstrated scores ranging from 3 to 7 points (on an 8-point scale). Prevalence of acute myocardial infarction ranged from 0.1 to 10.4% among the included studies.<h4>Interpretation</h4>There is insufficient population-based data describing the prevalence of acute myocardial infarction in sub-Saharan Africa. Well-designed registries and surveillance studies that capture the broad and diverse population with acute myocardial infarction in sub-Saharan Africa using common diagnostic criteria are critical in order to guide prevention and treatment strategies.<h4>Registration</h4>Registered in International Prospective Register of Systematic Reviews (PROSPERO) Database #CRD42012003161.https://doi.org/10.1371/journal.pone.0096688
spellingShingle Julian T Hertz
Joseph M Reardon
Clarissa G Rodrigues
Luciano de Andrade
Alexander T Limkakeng
Gerald S Bloomfield
Catherine A Lynch
Acute myocardial infarction in sub-Saharan Africa: the need for data.
PLoS ONE
title Acute myocardial infarction in sub-Saharan Africa: the need for data.
title_full Acute myocardial infarction in sub-Saharan Africa: the need for data.
title_fullStr Acute myocardial infarction in sub-Saharan Africa: the need for data.
title_full_unstemmed Acute myocardial infarction in sub-Saharan Africa: the need for data.
title_short Acute myocardial infarction in sub-Saharan Africa: the need for data.
title_sort acute myocardial infarction in sub saharan africa the need for data
url https://doi.org/10.1371/journal.pone.0096688
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