Initial pig developmental stage influences intestinal organoid growth but not cellular composition

Initial pig developmental stage influences intestinal organoid growth but not cellular composition

Abstract Background Intestinal organoids are promising tools in the context of animal experiment reduction but a thorough characterization of the impact of the origin of intestinal stem cells (ISC) on organoid phenotype is needed to routinely use this cellular model. Our objective was to evaluate th...

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Bibliographic Details
Main Authors: Camille Duchesne, Gwénaëlle Randuineau, Laurence Le Normand, Véronique Romé, Samia Laraqui, Alexis Pierre Arnaud, Gaëlle Boudry
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Animal Models and Experimental Medicine
Subjects:
colonoid
development
enteroid
organoid phenotype
piglet
Online Access:https://doi.org/10.1002/ame2.12512
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