Personalised Fractional-Order Autotuner for the Maintenance Phase of Anaesthesia Using Sine-Tests
The research field of clinical practice has experienced a substantial increase in the integration of information technology and control engineering, which includes the management of medication administration for general anaesthesia. The invasive nature of input signals is the reason why autotuning m...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-05-01
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| Series: | Fractal and Fractional |
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| Online Access: | https://www.mdpi.com/2504-3110/9/5/317 |
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| author | Marcian D. Mihai Isabela R. Birs Nicoleta E. Badau Erwin T. Hegedus Amani Ynineb Cristina I. Muresan |
| author_facet | Marcian D. Mihai Isabela R. Birs Nicoleta E. Badau Erwin T. Hegedus Amani Ynineb Cristina I. Muresan |
| author_sort | Marcian D. Mihai |
| collection | DOAJ |
| description | The research field of clinical practice has experienced a substantial increase in the integration of information technology and control engineering, which includes the management of medication administration for general anaesthesia. The invasive nature of input signals is the reason why autotuning methods are not widely used in this research field. This study proposes a non-invasive method using small-amplitude sine tests to estimate patient parameters, which allows the design of a personalised controller using an autotuning principle. The primary objective is to regulate the Bispectral Index through the administration of Propofol during the maintenance phase of anaesthesia, using a personalised fractional-order PID. This work aims to demonstrate the effectiveness of personalised control, which is facilitated by the proposed sine-based method. The closed-loop simulation results demonstrate the efficiency of the proposed approach. |
| format | Article |
| id | doaj-art-40cea2a15aaf42b5b50a1e353f97b04a |
| institution | DOAJ |
| issn | 2504-3110 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Fractal and Fractional |
| spelling | doaj-art-40cea2a15aaf42b5b50a1e353f97b04a2025-08-20T03:14:41ZengMDPI AGFractal and Fractional2504-31102025-05-019531710.3390/fractalfract9050317Personalised Fractional-Order Autotuner for the Maintenance Phase of Anaesthesia Using Sine-TestsMarcian D. Mihai0Isabela R. Birs1Nicoleta E. Badau2Erwin T. Hegedus3Amani Ynineb4Cristina I. Muresan5Department of Automation, Technical University of Cluj-Napoca, Memorandumului Street No 28, 400114 Cluj-Napoca, RomaniaDepartment of Automation, Technical University of Cluj-Napoca, Memorandumului Street No 28, 400114 Cluj-Napoca, RomaniaDepartment of Automation, Technical University of Cluj-Napoca, Memorandumului Street No 28, 400114 Cluj-Napoca, RomaniaDepartment of Automation, Technical University of Cluj-Napoca, Memorandumului Street No 28, 400114 Cluj-Napoca, RomaniaResearch Group on Dynamical Systems and Control, Department of Electromechanics, Systems and Metal Engineering, Ghent University, Tech Lane Science Park 125, 9052 Gent, BelgiumDepartment of Automation, Technical University of Cluj-Napoca, Memorandumului Street No 28, 400114 Cluj-Napoca, RomaniaThe research field of clinical practice has experienced a substantial increase in the integration of information technology and control engineering, which includes the management of medication administration for general anaesthesia. The invasive nature of input signals is the reason why autotuning methods are not widely used in this research field. This study proposes a non-invasive method using small-amplitude sine tests to estimate patient parameters, which allows the design of a personalised controller using an autotuning principle. The primary objective is to regulate the Bispectral Index through the administration of Propofol during the maintenance phase of anaesthesia, using a personalised fractional-order PID. This work aims to demonstrate the effectiveness of personalised control, which is facilitated by the proposed sine-based method. The closed-loop simulation results demonstrate the efficiency of the proposed approach.https://www.mdpi.com/2504-3110/9/5/317drug dosinganaesthesiaclosed-loop control of anaesthesiafractional-order controllersautotunerssine test |
| spellingShingle | Marcian D. Mihai Isabela R. Birs Nicoleta E. Badau Erwin T. Hegedus Amani Ynineb Cristina I. Muresan Personalised Fractional-Order Autotuner for the Maintenance Phase of Anaesthesia Using Sine-Tests Fractal and Fractional drug dosing anaesthesia closed-loop control of anaesthesia fractional-order controllers autotuners sine test |
| title | Personalised Fractional-Order Autotuner for the Maintenance Phase of Anaesthesia Using Sine-Tests |
| title_full | Personalised Fractional-Order Autotuner for the Maintenance Phase of Anaesthesia Using Sine-Tests |
| title_fullStr | Personalised Fractional-Order Autotuner for the Maintenance Phase of Anaesthesia Using Sine-Tests |
| title_full_unstemmed | Personalised Fractional-Order Autotuner for the Maintenance Phase of Anaesthesia Using Sine-Tests |
| title_short | Personalised Fractional-Order Autotuner for the Maintenance Phase of Anaesthesia Using Sine-Tests |
| title_sort | personalised fractional order autotuner for the maintenance phase of anaesthesia using sine tests |
| topic | drug dosing anaesthesia closed-loop control of anaesthesia fractional-order controllers autotuners sine test |
| url | https://www.mdpi.com/2504-3110/9/5/317 |
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