THE USE OF NORMOTHERMIC EXTRACORPOREAL PERFUSION IN SITU IN KIDNEY ASYSTOLIC DONORS
Deficit of donor organs is the limiting factor in organ transplantation. One way of solving this problem is the use of donors with sudden irreversible circulatory arrest. Obtaining organs from this category of donors is pos- sible only through the use of normothermic extracorporal perfusion in situ...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2010-06-01
|
| Series: | Вестник трансплантологии и искусственных органов |
| Subjects: | |
| Online Access: | https://journal.transpl.ru/vtio/article/view/339 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849691124258570240 |
|---|---|
| author | Y.. A. Shcherbuk S. F. Bagnenko A. E. Scvorzov I. V. Loginov A. N. Ananyev I. V. Ulyankina S. V. Eremich K. Y. Senchik O. N. Reznik |
| author_facet | Y.. A. Shcherbuk S. F. Bagnenko A. E. Scvorzov I. V. Loginov A. N. Ananyev I. V. Ulyankina S. V. Eremich K. Y. Senchik O. N. Reznik |
| author_sort | Y.. A. Shcherbuk |
| collection | DOAJ |
| description | Deficit of donor organs is the limiting factor in organ transplantation. One way of solving this problem is the use of donors with sudden irreversible circulatory arrest. Obtaining organs from this category of donors is pos- sible only through the use of normothermic extracorporal perfusion in situ (NECP) with oxygenation and leu- cocyte depletion. The article presents the implementation of NECP in 11 uncontrolled non heart beating donor (uNHBD) kidneys (age of 43,1 ± 2,98 years) and the results of transplantation in 22 recipients of such transplants in comparison with the results of the 20 recipients of kidney transplants from 20 donors to the death of the brain (age 45,65 ± 1,8 years). Despite the initially high rate of delayed function and more significant number of hemo- dialysis in uNHBD group (group of investigation), serum creatinine at 21st day was the same level as in BDD group (comparison group): 0,198 ± 0,002 mmol/L and 0,151 ± 0,002 mmol/L (p > 0,05). The use of NECP with oxygenation and leucocyte depletion is an effective practice for recovery kidney from donors with a sudden ir- reversible circulatory arrest with warm ischemic time one hour and more before the operation explantation. |
| format | Article |
| id | doaj-art-40cdc540115c48fe8cd50a575bb78a6c |
| institution | DOAJ |
| issn | 1995-1191 |
| language | Russian |
| publishDate | 2010-06-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Вестник трансплантологии и искусственных органов |
| spelling | doaj-art-40cdc540115c48fe8cd50a575bb78a6c2025-08-20T03:21:07ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912010-06-01124111810.15825/1995-1191-2010-4-11-18282THE USE OF NORMOTHERMIC EXTRACORPOREAL PERFUSION IN SITU IN KIDNEY ASYSTOLIC DONORSY.. A. Shcherbuk0S. F. Bagnenko1A. E. Scvorzov2I. V. Loginov3A. N. Ananyev4I. V. Ulyankina5S. V. Eremich6K. Y. Senchik7O. N. Reznik8I.I. Djanelidze State Research Institute for Emergency, Saint-PetersburgI.I. Djanelidze State Research Institute for Emergency, Saint-PetersburgI.I. Djanelidze State Research Institute for Emergency, Saint-PetersburgI.I. Djanelidze State Research Institute for Emergency, Saint-PetersburgI.I. Djanelidze State Research Institute for Emergency, Saint-PetersburgI.I. Djanelidze State Research Institute for Emergency, Saint-PetersburgI.I. Djanelidze State Research Institute for Emergency, Saint-PetersburgCentral Research Institute of Robotics and Technical Cybernetics, St. PetersburgI.I. Djanelidze State Research Institute for Emergency, Saint-PetersburgDeficit of donor organs is the limiting factor in organ transplantation. One way of solving this problem is the use of donors with sudden irreversible circulatory arrest. Obtaining organs from this category of donors is pos- sible only through the use of normothermic extracorporal perfusion in situ (NECP) with oxygenation and leu- cocyte depletion. The article presents the implementation of NECP in 11 uncontrolled non heart beating donor (uNHBD) kidneys (age of 43,1 ± 2,98 years) and the results of transplantation in 22 recipients of such transplants in comparison with the results of the 20 recipients of kidney transplants from 20 donors to the death of the brain (age 45,65 ± 1,8 years). Despite the initially high rate of delayed function and more significant number of hemo- dialysis in uNHBD group (group of investigation), serum creatinine at 21st day was the same level as in BDD group (comparison group): 0,198 ± 0,002 mmol/L and 0,151 ± 0,002 mmol/L (p > 0,05). The use of NECP with oxygenation and leucocyte depletion is an effective practice for recovery kidney from donors with a sudden ir- reversible circulatory arrest with warm ischemic time one hour and more before the operation explantation.https://journal.transpl.ru/vtio/article/view/339uncontrolled donors after cardiac deathwarm ischemic timeleucocytes depletionnormothermic extracorporal perfusion in situ. |
| spellingShingle | Y.. A. Shcherbuk S. F. Bagnenko A. E. Scvorzov I. V. Loginov A. N. Ananyev I. V. Ulyankina S. V. Eremich K. Y. Senchik O. N. Reznik THE USE OF NORMOTHERMIC EXTRACORPOREAL PERFUSION IN SITU IN KIDNEY ASYSTOLIC DONORS Вестник трансплантологии и искусственных органов uncontrolled donors after cardiac death warm ischemic time leucocytes depletion normothermic extracorporal perfusion in situ. |
| title | THE USE OF NORMOTHERMIC EXTRACORPOREAL PERFUSION IN SITU IN KIDNEY ASYSTOLIC DONORS |
| title_full | THE USE OF NORMOTHERMIC EXTRACORPOREAL PERFUSION IN SITU IN KIDNEY ASYSTOLIC DONORS |
| title_fullStr | THE USE OF NORMOTHERMIC EXTRACORPOREAL PERFUSION IN SITU IN KIDNEY ASYSTOLIC DONORS |
| title_full_unstemmed | THE USE OF NORMOTHERMIC EXTRACORPOREAL PERFUSION IN SITU IN KIDNEY ASYSTOLIC DONORS |
| title_short | THE USE OF NORMOTHERMIC EXTRACORPOREAL PERFUSION IN SITU IN KIDNEY ASYSTOLIC DONORS |
| title_sort | use of normothermic extracorporeal perfusion in situ in kidney asystolic donors |
| topic | uncontrolled donors after cardiac death warm ischemic time leucocytes depletion normothermic extracorporal perfusion in situ. |
| url | https://journal.transpl.ru/vtio/article/view/339 |
| work_keys_str_mv | AT yashcherbuk theuseofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT sfbagnenko theuseofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT aescvorzov theuseofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT ivloginov theuseofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT anananyev theuseofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT ivulyankina theuseofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT sveremich theuseofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT kysenchik theuseofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT onreznik theuseofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT yashcherbuk useofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT sfbagnenko useofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT aescvorzov useofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT ivloginov useofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT anananyev useofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT ivulyankina useofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT sveremich useofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT kysenchik useofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors AT onreznik useofnormothermicextracorporealperfusioninsituinkidneyasystolicdonors |