A genome-wide association study identifies genetic determinants of hemoglobin glycation index with implications across sex and ethnicity

A genome-wide association study identifies genetic determinants of hemoglobin glycation index with implications across sex and ethnicity

IntroductionWe investigated the genetic determinants of variation in the hemoglobin glycation index (HGI), an emerging biomarker for the risk of diabetes complications.MethodsWe conducted a genome-wide association study (GWAS) for HGI in the Action to Control Cardiovascular Risk in Diabetes (ACCORD)...

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Bibliographic Details
Main Authors: John S. House, Joseph H. Breeyear, Farida S. Akhtari, Violet Evans, John B. Buse, James Hempe, Alessandro Doria, Josyf C. Mychaleckyi, Vivian Fonseca, Mengyao Shi, Changwei Li, Shuqian Liu, Tanika N. Kelly, Daniel Rotroff, Alison A. Motsinger-Reif
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Endocrinology
Subjects:
hemoglobin glycation index
HGI
HbA1c
ACCORD
ARIC
GWAS
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1473329/full
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