High expression of SMPD4 promotes liver cancer and is associated with poor prognosis

High expression of SMPD4 promotes liver cancer and is associated with poor prognosis

Abstract Objectives The expression of sphingomyelin phosphodiesterase 4 (SMPD4), a neutral sphingomyelin enzyme, is intricately associated with tumorigenesis and progression. However, its role in hepatocellular carcinoma (HCC) remains unclear. This study mainly reports the expression, prognostic val...

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Bibliographic Details
Main Authors: Rongyue Wang, Ting Wang, Yanze Su, Zhiheng Lin, Xiaoping Liu, Yuanjun Jiao, Jikui Liu, Erbao Chen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Research Notes
Subjects:
Hepatocellular carcinoma
SMPD4
Prognosis
Immune infiltration
Cell cycle
Online Access:https://doi.org/10.1186/s13104-025-07212-4
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