Big Data in traumatic brain injury; promise and challenges

Traumatic brain injury (TBI) is a spectrum disease of overwhelming complexity, the research of which generates enormous amounts of structured, semi-structured and unstructured data. This resulting big data has tremendous potential to be mined for valuable information regarding the “most complex dise...

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Main Authors: Denes V Agoston, Dianne Langford
Format: Article
Language:English
Published: Aldus Press 2017-12-01
Series:Concussion
Subjects:
Online Access:https://www.futuremedicine.com/doi/10.2217/cnc-2016-0013
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author Denes V Agoston
Dianne Langford
author_facet Denes V Agoston
Dianne Langford
author_sort Denes V Agoston
collection DOAJ
description Traumatic brain injury (TBI) is a spectrum disease of overwhelming complexity, the research of which generates enormous amounts of structured, semi-structured and unstructured data. This resulting big data has tremendous potential to be mined for valuable information regarding the “most complex disease of the most complex organ”. Big data analyses require specialized big data analytics applications, machine learning and artificial intelligence platforms to reveal associations, trends, correlations and patterns not otherwise realized by current analytical approaches. The intersection of potential data sources between experimental TBI and clinical TBI research presents inherent challenges for setting parameters for the generation of common data elements and to mine existing legacy data that would allow highly translatable big data analyses. In order to successfully utilize big data analyses in TBI, we must be willing to accept the messiness of data, collect and store all data and give up causation for correlation. In this context, coupling the big data approach to established clinical and pre-clinical data sources will transform current practices for triage, diagnosis, treatment and prognosis into highly integrated evidence-based patient care.
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spelling doaj-art-40c30e8bdd6541bc85d0fe1fed6d68fd2025-08-20T02:16:29ZengAldus PressConcussion2056-32992017-12-012410.2217/cnc-2016-0013Big Data in traumatic brain injury; promise and challengesDenes V Agoston0Dianne Langford11Department of Anatomy, Physiology & Genetics, Uniformed Services University, Bethesda, MD 20814, USA3Department of Neuroscience, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USATraumatic brain injury (TBI) is a spectrum disease of overwhelming complexity, the research of which generates enormous amounts of structured, semi-structured and unstructured data. This resulting big data has tremendous potential to be mined for valuable information regarding the “most complex disease of the most complex organ”. Big data analyses require specialized big data analytics applications, machine learning and artificial intelligence platforms to reveal associations, trends, correlations and patterns not otherwise realized by current analytical approaches. The intersection of potential data sources between experimental TBI and clinical TBI research presents inherent challenges for setting parameters for the generation of common data elements and to mine existing legacy data that would allow highly translatable big data analyses. In order to successfully utilize big data analyses in TBI, we must be willing to accept the messiness of data, collect and store all data and give up causation for correlation. In this context, coupling the big data approach to established clinical and pre-clinical data sources will transform current practices for triage, diagnosis, treatment and prognosis into highly integrated evidence-based patient care.https://www.futuremedicine.com/doi/10.2217/cnc-2016-0013artificial intelligencebig databig data analyticsmachine learningtraumatic brain injury
spellingShingle Denes V Agoston
Dianne Langford
Big Data in traumatic brain injury; promise and challenges
Concussion
artificial intelligence
big data
big data analytics
machine learning
traumatic brain injury
title Big Data in traumatic brain injury; promise and challenges
title_full Big Data in traumatic brain injury; promise and challenges
title_fullStr Big Data in traumatic brain injury; promise and challenges
title_full_unstemmed Big Data in traumatic brain injury; promise and challenges
title_short Big Data in traumatic brain injury; promise and challenges
title_sort big data in traumatic brain injury promise and challenges
topic artificial intelligence
big data
big data analytics
machine learning
traumatic brain injury
url https://www.futuremedicine.com/doi/10.2217/cnc-2016-0013
work_keys_str_mv AT denesvagoston bigdataintraumaticbraininjurypromiseandchallenges
AT diannelangford bigdataintraumaticbraininjurypromiseandchallenges