Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface
ABSTRACT Tuberculosis (TB) is the leading cause of infectious disease death and lacks a vaccine capable of protecting adults from pulmonary TB. The bacterial surface is a critical interface that shapes host-pathogen interactions. Several knowledge gaps persist in our understanding of Mycobacterium t...
Saved in:
Main Authors: | Bianca A. Lepe, Christine R. Zheng, Owen K. Leddy, Benjamin L. Allsup, Sydney L. Solomon, Bryan D. Bryson |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2025-02-01
|
Series: | Microbiology Spectrum |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/spectrum.02277-24 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Antibodies against neuronal surface antigens in acute stroke: a systematic review and meta-analysis
by: Matteo Paolucci, et al.
Published: (2025-01-01) -
Tumor-specific cytosol-penetrating antibodies for antigen- and TME-dependent intracellular cargo delivery
by: Carolin Sophie Dombrowsky, et al.
Published: (2025-03-01) -
Prevalence of transfusion-transmitted infection and reactive donor response rate in a tertiary care hospital in South India: A retrospective observational study
by: Kingsley Simon, et al.
Published: (2024-12-01) -
Efficient Predictor for Immunotherapy Efficacy: Detecting Pan‐Clones Effector Tumor Antigen‐Specific T Cells in Blood by Nanoparticles Loading Whole Tumor Antigens
by: Weibiao Zeng, et al.
Published: (2025-01-01) -
Immunogenicity and protective efficacy of a multi-antigenic adenovirus-based vaccine candidate against Mycobacterium tuberculosis
by: Jin-Seung Yun, et al.
Published: (2025-01-01)