BIOLOGYCAL IMUNOMODULATORS IN THE COMPLEX THERAPY OF INFECTIOUS MONONUCLEOSIS IN CHILDREN

80 patients were observed with infectious mononucleosis (IM) from 2 to 12 years. Diagnosis was confirmed by the definition of M- and G-antibodies to EBV, CMV, HHV6, PCR DNA these viruses, bacteriological and blood-tests investigations. 40 patients was given bifidumbacterin forte 45—90 doses a day an...

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Main Authors: A. G. Bokovoy, I. V. Kovalev, L. F. Makkaveeva, O. A. Volodina, A. A. Komarov, A. Yu. Medkova, N. B. Tanina
Format: Article
Language:Russian
Published: LLC "Diagnostics and Vaccines" 2015-09-01
Series:Детские инфекции (Москва)
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Online Access:https://detinf.elpub.ru/jour/article/view/81
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author A. G. Bokovoy
I. V. Kovalev
L. F. Makkaveeva
O. A. Volodina
A. A. Komarov
A. Yu. Medkova
N. B. Tanina
author_facet A. G. Bokovoy
I. V. Kovalev
L. F. Makkaveeva
O. A. Volodina
A. A. Komarov
A. Yu. Medkova
N. B. Tanina
author_sort A. G. Bokovoy
collection DOAJ
description 80 patients were observed with infectious mononucleosis (IM) from 2 to 12 years. Diagnosis was confirmed by the definition of M- and G-antibodies to EBV, CMV, HHV6, PCR DNA these viruses, bacteriological and blood-tests investigations. 40 patients was given bifidumbacterin forte 45—90 doses a day and cycloferon 8 mg/kg/weight a day(1-st group). The comparison group consisted of 40 patients with IM receiving symptomatic therapy and antibiotics (2-nd group). The observations shoved significant decreasing of length of clinical symptoms IM in the 1-st group with comparison of the 2-nd group. The obtained results allow to recommend bifidumbacterin forte and cycloferon in the complex therapy in children with infectious mononucleosis.
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issn 2072-8107
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publishDate 2015-09-01
publisher LLC "Diagnostics and Vaccines"
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series Детские инфекции (Москва)
spelling doaj-art-40bb99dba0374179b29bd575ffc063652025-08-20T03:15:22ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072015-09-01141303510.22627/2072-8107-2015-14-1-3-881BIOLOGYCAL IMUNOMODULATORS IN THE COMPLEX THERAPY OF INFECTIOUS MONONUCLEOSIS IN CHILDRENA. G. Bokovoy0I. V. Kovalev1L. F. Makkaveeva2O. A. Volodina3A. A. Komarov4A. Yu. Medkova5N. B. Tanina6Сentral Clinical Hospital of Government Russian Federation, MoskowСentral Clinical Hospital of Government Russian Federation, MoskowСentral Clinical Hospital of Government Russian Federation, MoskowСentral Clinical Hospital of Government Russian Federation, MoskowСentral Clinical Hospital of Government Russian Federation, MoskowСentral Clinical Hospital of Government Russian Federation, MoskowСentral Clinical Hospital of Government Russian Federation, Moskow80 patients were observed with infectious mononucleosis (IM) from 2 to 12 years. Diagnosis was confirmed by the definition of M- and G-antibodies to EBV, CMV, HHV6, PCR DNA these viruses, bacteriological and blood-tests investigations. 40 patients was given bifidumbacterin forte 45—90 doses a day and cycloferon 8 mg/kg/weight a day(1-st group). The comparison group consisted of 40 patients with IM receiving symptomatic therapy and antibiotics (2-nd group). The observations shoved significant decreasing of length of clinical symptoms IM in the 1-st group with comparison of the 2-nd group. The obtained results allow to recommend bifidumbacterin forte and cycloferon in the complex therapy in children with infectious mononucleosis.https://detinf.elpub.ru/jour/article/view/81infectious mononucleosisbifidumbacterin fortecycloferonchildren
spellingShingle A. G. Bokovoy
I. V. Kovalev
L. F. Makkaveeva
O. A. Volodina
A. A. Komarov
A. Yu. Medkova
N. B. Tanina
BIOLOGYCAL IMUNOMODULATORS IN THE COMPLEX THERAPY OF INFECTIOUS MONONUCLEOSIS IN CHILDREN
Детские инфекции (Москва)
infectious mononucleosis
bifidumbacterin forte
cycloferon
children
title BIOLOGYCAL IMUNOMODULATORS IN THE COMPLEX THERAPY OF INFECTIOUS MONONUCLEOSIS IN CHILDREN
title_full BIOLOGYCAL IMUNOMODULATORS IN THE COMPLEX THERAPY OF INFECTIOUS MONONUCLEOSIS IN CHILDREN
title_fullStr BIOLOGYCAL IMUNOMODULATORS IN THE COMPLEX THERAPY OF INFECTIOUS MONONUCLEOSIS IN CHILDREN
title_full_unstemmed BIOLOGYCAL IMUNOMODULATORS IN THE COMPLEX THERAPY OF INFECTIOUS MONONUCLEOSIS IN CHILDREN
title_short BIOLOGYCAL IMUNOMODULATORS IN THE COMPLEX THERAPY OF INFECTIOUS MONONUCLEOSIS IN CHILDREN
title_sort biologycal imunomodulators in the complex therapy of infectious mononucleosis in children
topic infectious mononucleosis
bifidumbacterin forte
cycloferon
children
url https://detinf.elpub.ru/jour/article/view/81
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