Monitoring mRNA vaccine antigen expression in vivo using PET/CT

Monitoring mRNA vaccine antigen expression in vivo using PET/CT

Abstract Noninvasive visualization of the distribution and persistence of mRNA vaccine antigen expression in mammalian systems has implications for the development and evaluation of future mRNA vaccines. Here, we genetically fuse E. coli dihydrofolate reductase (eDHFR) to the delta furin diproline m...

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Main Authors: Gabrielle S. Blizard, Garima Dwivedi, Yi-Gen Pan, Catherine Hou, Jean M. Etersque, Hooda Said, Anik Chevrier, Marc Lavertu, Houping Ni, Benjamin Davis, Ying Tam, Quy Cao, Robert H. Mach, Drew Weissman, Mohamad-Gabriel Alameh, Mark A. Sellmyer
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57446-w
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