Development and application of GlycanDIA workflow for glycomic analysis

Development and application of GlycanDIA workflow for glycomic analysis

Abstract Glycans modify protein, lipid, and even RNA molecules to form the regulatory outer coat on cells called the glycocalyx. The changes in glycosylation have been linked to the initiation and progression of many diseases. Herein, we report a DIA-based glycomic workflow, termed GlycanDIA, to ide...

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Main Authors: Yixuan Xie, Xingyu Liu, Li Yi, Shunyang Wang, Zongtao Lin, Chenfeng Zhao, Siyu Chen, Faith M. Robison, Benson M. George, Carlito B. Lebrilla, Ryan A. Flynn, Benjamin A. Garcia
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61473-y
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