Sleep timing in flies from “adolescence” to adulthood
The aim of the present study was to assess sleep timing in Drosophila melanogaster at different ages, within the setting of an enforced schedule of varying light-dark stimuli, simulating light exposure variations between four typical office working days and one free day spent outside by a human, for...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Fly |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/19336934.2024.2448022 |
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| author | Esther D. Domenie Paola Cusumano Sara Montagnese Rodolfo Costa |
| author_facet | Esther D. Domenie Paola Cusumano Sara Montagnese Rodolfo Costa |
| author_sort | Esther D. Domenie |
| collection | DOAJ |
| description | The aim of the present study was to assess sleep timing in Drosophila melanogaster at different ages, within the setting of an enforced schedule of varying light-dark stimuli, simulating light exposure variations between four typical office working days and one free day spent outside by a human, for a total of 30 days. Locomotor activity recording started when male flies were 3 days old. Flies exhibited a bimodal activity pattern, with a morning and an evening peak, and clear anticipation of the lights on and lights off transitions. From experimental day 10 (i.e. 12-day-old flies) onwards, a decrease in activity counts/increase in sleep amount were observed. On free days, a rise in activity counts and a reduction in sleep amount during the lights on interval was observed and was also present, albeit less obvious, on the subsequent working day during the lights off interval. A progressive delay in sleep onset was observed in the first days of the experiment, peaking on day 4 (i.e. 6-day-old flies), after which sleep onset timing gradually advanced. A delay in sleep offset was also observed for the first 13 days of the experiment, after which sleep offset stabilized. In conclusion, ‘adolescent’ flies exhibited changes in sleep timing that were reminiscent of those of human adolescents. |
| format | Article |
| id | doaj-art-40afc73ff2474710ae5ba46c58e70aa2 |
| institution | OA Journals |
| issn | 1933-6934 1933-6942 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Fly |
| spelling | doaj-art-40afc73ff2474710ae5ba46c58e70aa22025-08-20T02:36:53ZengTaylor & Francis GroupFly1933-69341933-69422025-12-0119110.1080/19336934.2024.2448022Sleep timing in flies from “adolescence” to adulthoodEsther D. Domenie0Paola Cusumano1Sara Montagnese2Rodolfo Costa3Department of Medicine, University of Padova, Padova, ItalyDepartment of Biology, University of Padova, Padova, ItalyDepartment of Medicine, University of Padova, Padova, ItalyChronobiology Section, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UKThe aim of the present study was to assess sleep timing in Drosophila melanogaster at different ages, within the setting of an enforced schedule of varying light-dark stimuli, simulating light exposure variations between four typical office working days and one free day spent outside by a human, for a total of 30 days. Locomotor activity recording started when male flies were 3 days old. Flies exhibited a bimodal activity pattern, with a morning and an evening peak, and clear anticipation of the lights on and lights off transitions. From experimental day 10 (i.e. 12-day-old flies) onwards, a decrease in activity counts/increase in sleep amount were observed. On free days, a rise in activity counts and a reduction in sleep amount during the lights on interval was observed and was also present, albeit less obvious, on the subsequent working day during the lights off interval. A progressive delay in sleep onset was observed in the first days of the experiment, peaking on day 4 (i.e. 6-day-old flies), after which sleep onset timing gradually advanced. A delay in sleep offset was also observed for the first 13 days of the experiment, after which sleep offset stabilized. In conclusion, ‘adolescent’ flies exhibited changes in sleep timing that were reminiscent of those of human adolescents.https://www.tandfonline.com/doi/10.1080/19336934.2024.2448022Drosophila melanogasterlocomotor activitysleep timingagelight |
| spellingShingle | Esther D. Domenie Paola Cusumano Sara Montagnese Rodolfo Costa Sleep timing in flies from “adolescence” to adulthood Fly Drosophila melanogaster locomotor activity sleep timing age light |
| title | Sleep timing in flies from “adolescence” to adulthood |
| title_full | Sleep timing in flies from “adolescence” to adulthood |
| title_fullStr | Sleep timing in flies from “adolescence” to adulthood |
| title_full_unstemmed | Sleep timing in flies from “adolescence” to adulthood |
| title_short | Sleep timing in flies from “adolescence” to adulthood |
| title_sort | sleep timing in flies from adolescence to adulthood |
| topic | Drosophila melanogaster locomotor activity sleep timing age light |
| url | https://www.tandfonline.com/doi/10.1080/19336934.2024.2448022 |
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