Discovery of plasma proteins and metabolites associated with left ventricular cardiac dysfunction in pan-cancer patients

Discovery of plasma proteins and metabolites associated with left ventricular cardiac dysfunction in pan-cancer patients

Abstract Background Cancer-therapy related cardiac dysfunction (CTRCD) remains a significant cause of morbidity and mortality in cancer survivors. In this study, we aimed to identify differential plasma proteins and metabolites associated with left ventricular dysfunction (LVD) in cancer patients. M...

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Bibliographic Details
Main Authors: Jessica C. Lal, Michelle Z. Fang, Muzna Hussain, Abel Abraham, Reina Tonegawa-Kuji, Yuan Hou, Mina K. Chung, Patrick Collier, Feixiong Cheng
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Cardio-Oncology
Subjects:
Cardiotoxicity
Machine learning models
Multi-omics
Plasma proteomics
Plasma metabolomics
Online Access:https://doi.org/10.1186/s40959-025-00309-6
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