The Importance of Mitochondrial DNA in Aging and Cancer

Mitochondrial dysfunction has been implicated in premature aging, age-related diseases, and tumor initiation and progression. Alterations of the mitochondrial genome accumulate both in aging tissue and tumors. This paper describes our contemporary view of mechanisms by which alterations of the mitoc...

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Bibliographic Details
Main Authors: Claus Desler, Maiken Lise Marcker, Keshav K. Singh, Lene Juel Rasmussen
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Aging Research
Online Access:http://dx.doi.org/10.4061/2011/407536
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