Effect of histone demethylase KDM5B on long-term cognitive impairment in neonatal rats induced by sevoflurane

Effect of histone demethylase KDM5B on long-term cognitive impairment in neonatal rats induced by sevoflurane

IntroductionWhether repeated inhalation of sevoflurane during the neonatal period causes long-term learning and memory impairments in humans is unclear. Some recent investigations have indicated that general anesthesia drugs affect histone methylation modification and may further affect learning and...

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Bibliographic Details
Main Authors: Yanhong Wang, Yun Chen, Mengxiao Zhang, Chengdong Yuan, Yu Zhang, Xingjian Liu, Yi Zhang, Xiaoli Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
sevoflurane
cognitive
histone methylation
hippocampus
neonatal
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1459358/full
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