T-cell responses induced by SARS-CoV-2 index-virus nanoparticle protein vaccine to the ancestral and omicron variants 6 months following primary vaccination

T-cell responses induced by SARS-CoV-2 index-virus nanoparticle protein vaccine to the ancestral and omicron variants 6 months following primary vaccination

Abstract Background The SARS-CoV-2 index-virus nanoparticle protein vaccine (NVX-CoV2373) induces humoral and cell-mediated immune responses that protect against severe COVID-19, including from SARS-CoV-2 variants. Limited information exists on NVX-CoV2373–induced cell-mediated immune responses to a...

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Main Authors: William C. McMahon, Gaurav Kwatra, Marta C. Nunes, Alane Izu, Anthonet L. Koen, Johann Greffrath, Sharon Shalekoff, Caroline T. Tiemessen, Vivek Shinde, Chijioke Bennett, Shabir A. Madhi
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00941-4
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