Accuracy of Transverse Cerebellar Diameter in Estimating Gestational Age in the Second and Third Trimester: A Prospective Study in Saudi Arabia
<b>Background:</b> Failure to accurately estimate gestational age remains an important dilemma for optimal evidence-based antenatal care. Currently, when the last menstrual period (LMP) is unknown, ultrasonography measurement is the best method for estimating gestational age (GA). This s...
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2025-04-01
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| author | Awadia Gareeballah Sultan Abdulwadoud Alshoabi Ashwaq Mohammed Alharbi Mashael Hisham Alali Wed Mubarak Alraddadi Fadwa Mohammed Al-Ahmadi Reem Mustafa Dwaidy Rahaf Alamri Wessal Abdulkarim Alkhoudair Walaa Alsharif Maisa Elzaki Amirah Faisal Alsaedi Moawia Gameraddin Osama Mohammed Abdulaal Mohammed Adam |
| author_facet | Awadia Gareeballah Sultan Abdulwadoud Alshoabi Ashwaq Mohammed Alharbi Mashael Hisham Alali Wed Mubarak Alraddadi Fadwa Mohammed Al-Ahmadi Reem Mustafa Dwaidy Rahaf Alamri Wessal Abdulkarim Alkhoudair Walaa Alsharif Maisa Elzaki Amirah Faisal Alsaedi Moawia Gameraddin Osama Mohammed Abdulaal Mohammed Adam |
| author_sort | Awadia Gareeballah |
| collection | DOAJ |
| description | <b>Background:</b> Failure to accurately estimate gestational age remains an important dilemma for optimal evidence-based antenatal care. Currently, when the last menstrual period (LMP) is unknown, ultrasonography measurement is the best method for estimating gestational age (GA). This study aims to assess the feasibility and accuracy of ultrasonography measurement of the transverse cerebellar diameter (TCD) to deduce fetal GA after 13 weeks of gestation. <b>Methods:</b> A prospective study was conducted on 384 normal singleton pregnancies. Demographic information and biometric measurements, including TCD, were collected using a data sheet. The data were then analyzed using SPSS version 27, DATAtab, and the R program. <b>Results:</b> The study found a strong significant association between GA based on TCD and the LMP, GA based on femur length (FL), GA based on biparietal diameter (BPD), GA based on abdominal circumference (AC), and GA based on the average gestational age (AVG) (r = 0.976, 0.970, 0.966, 0.968, and 0.984, respectively, <i>p</i> < 0.001). Furthermore, there was perfect agreement between GA estimated using TCD and GA based on LMP, with a mean difference of 0.41 weeks and upper and lower limits of agreement of −1.43 to 2.26 weeks. <b>Conclusions:</b> Ultrasonography measurements of the TCD accurately predict gestational age with excellent concordance with GA based on the LMP, FL, AC, and BPD. TCD can be used as a reliable estimator of GA in the second and third trimesters of pregnancy with the benefit of its brain-sparing effect in fetuses of fetal intrauterine growth restriction pregnancies. Combining TCD with FL, BPD, and AC provides the most accurate method of GA prediction. |
| format | Article |
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| spelling | doaj-art-4087d5f8c314495cb6e7502aed19f1d32025-08-20T01:49:20ZengMDPI AGDiagnostics2075-44182025-04-01159113010.3390/diagnostics15091130Accuracy of Transverse Cerebellar Diameter in Estimating Gestational Age in the Second and Third Trimester: A Prospective Study in Saudi ArabiaAwadia Gareeballah0Sultan Abdulwadoud Alshoabi1Ashwaq Mohammed Alharbi2Mashael Hisham Alali3Wed Mubarak Alraddadi4Fadwa Mohammed Al-Ahmadi5Reem Mustafa Dwaidy6Rahaf Alamri7Wessal Abdulkarim Alkhoudair8Walaa Alsharif9Maisa Elzaki10Amirah Faisal Alsaedi11Moawia Gameraddin12Osama Mohammed Abdulaal13Mohammed Adam14Department of Diagnostic Radiology, College of Applied Medical Sciences, Taibah University, Al-Madinah Al-Munawwarah 42353, Saudi ArabiaDepartment of Diagnostic Radiology, College of Applied Medical Sciences, Taibah University, Al-Madinah Al-Munawwarah 42353, Saudi ArabiaDepartment of Diagnostic Radiology, College of Applied Medical Sciences, Taibah University, Al-Madinah Al-Munawwarah 42353, Saudi ArabiaDepartment of Diagnostic Radiology, College of Applied Medical Sciences, Taibah University, Al-Madinah Al-Munawwarah 42353, Saudi ArabiaDepartment of Diagnostic Radiology, College of Applied Medical Sciences, Taibah University, Al-Madinah Al-Munawwarah 42353, Saudi ArabiaKing Salman Medical City-Maternity and Children’s Hospital, Al-Madina Al-Munawwarah 42319, Saudi ArabiaKing Salman Medical City-Maternity and Children’s Hospital, Al-Madina Al-Munawwarah 42319, Saudi ArabiaKing Salman Medical City-Maternity and Children’s Hospital, Al-Madina Al-Munawwarah 42319, Saudi ArabiaKing Salman Medical City-Maternity and Children’s Hospital, Al-Madina Al-Munawwarah 42319, Saudi ArabiaDepartment of Diagnostic Radiology, College of Applied Medical Sciences, Taibah University, Al-Madinah Al-Munawwarah 42353, Saudi ArabiaDepartment of Diagnostic Radiology, College of Applied Medical Sciences, Taibah University, Al-Madinah Al-Munawwarah 42353, Saudi ArabiaDepartment of Diagnostic Radiology, College of Applied Medical Sciences, Taibah University, Al-Madinah Al-Munawwarah 42353, Saudi ArabiaDepartment of Diagnostic Radiology, College of Applied Medical Sciences, Taibah University, Al-Madinah Al-Munawwarah 42353, Saudi ArabiaDepartment of Diagnostic Radiology, College of Applied Medical Sciences, Taibah University, Al-Madinah Al-Munawwarah 42353, Saudi ArabiaDepartment of Radiological Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia<b>Background:</b> Failure to accurately estimate gestational age remains an important dilemma for optimal evidence-based antenatal care. Currently, when the last menstrual period (LMP) is unknown, ultrasonography measurement is the best method for estimating gestational age (GA). This study aims to assess the feasibility and accuracy of ultrasonography measurement of the transverse cerebellar diameter (TCD) to deduce fetal GA after 13 weeks of gestation. <b>Methods:</b> A prospective study was conducted on 384 normal singleton pregnancies. Demographic information and biometric measurements, including TCD, were collected using a data sheet. The data were then analyzed using SPSS version 27, DATAtab, and the R program. <b>Results:</b> The study found a strong significant association between GA based on TCD and the LMP, GA based on femur length (FL), GA based on biparietal diameter (BPD), GA based on abdominal circumference (AC), and GA based on the average gestational age (AVG) (r = 0.976, 0.970, 0.966, 0.968, and 0.984, respectively, <i>p</i> < 0.001). Furthermore, there was perfect agreement between GA estimated using TCD and GA based on LMP, with a mean difference of 0.41 weeks and upper and lower limits of agreement of −1.43 to 2.26 weeks. <b>Conclusions:</b> Ultrasonography measurements of the TCD accurately predict gestational age with excellent concordance with GA based on the LMP, FL, AC, and BPD. TCD can be used as a reliable estimator of GA in the second and third trimesters of pregnancy with the benefit of its brain-sparing effect in fetuses of fetal intrauterine growth restriction pregnancies. Combining TCD with FL, BPD, and AC provides the most accurate method of GA prediction.https://www.mdpi.com/2075-4418/15/9/1130gestational age (GA)last menstrual period (LMP)ultrasonography fetal measurementstransverse cerebellar diameter (TCD)biparietal diameter (BPD)femur length (FL) |
| spellingShingle | Awadia Gareeballah Sultan Abdulwadoud Alshoabi Ashwaq Mohammed Alharbi Mashael Hisham Alali Wed Mubarak Alraddadi Fadwa Mohammed Al-Ahmadi Reem Mustafa Dwaidy Rahaf Alamri Wessal Abdulkarim Alkhoudair Walaa Alsharif Maisa Elzaki Amirah Faisal Alsaedi Moawia Gameraddin Osama Mohammed Abdulaal Mohammed Adam Accuracy of Transverse Cerebellar Diameter in Estimating Gestational Age in the Second and Third Trimester: A Prospective Study in Saudi Arabia Diagnostics gestational age (GA) last menstrual period (LMP) ultrasonography fetal measurements transverse cerebellar diameter (TCD) biparietal diameter (BPD) femur length (FL) |
| title | Accuracy of Transverse Cerebellar Diameter in Estimating Gestational Age in the Second and Third Trimester: A Prospective Study in Saudi Arabia |
| title_full | Accuracy of Transverse Cerebellar Diameter in Estimating Gestational Age in the Second and Third Trimester: A Prospective Study in Saudi Arabia |
| title_fullStr | Accuracy of Transverse Cerebellar Diameter in Estimating Gestational Age in the Second and Third Trimester: A Prospective Study in Saudi Arabia |
| title_full_unstemmed | Accuracy of Transverse Cerebellar Diameter in Estimating Gestational Age in the Second and Third Trimester: A Prospective Study in Saudi Arabia |
| title_short | Accuracy of Transverse Cerebellar Diameter in Estimating Gestational Age in the Second and Third Trimester: A Prospective Study in Saudi Arabia |
| title_sort | accuracy of transverse cerebellar diameter in estimating gestational age in the second and third trimester a prospective study in saudi arabia |
| topic | gestational age (GA) last menstrual period (LMP) ultrasonography fetal measurements transverse cerebellar diameter (TCD) biparietal diameter (BPD) femur length (FL) |
| url | https://www.mdpi.com/2075-4418/15/9/1130 |
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