Acetyltransferase NAT10 inhibits T-cell immunity and promotes nasopharyngeal carcinoma progression through DDX5/HMGB1 axis

Acetyltransferase NAT10 inhibits T-cell immunity and promotes nasopharyngeal carcinoma progression through DDX5/HMGB1 axis

Background Immunosuppression significantly contributes to treatment failure in nasopharyngeal carcinoma (NPC). Messenger RNA (mRNA) modifications such as methylation and acetylation play crucial roles in immunosuppression. However, N4-acetylcytidine (ac4C), the only acetylation modification event ha...

Full description

Saved in:
Bibliographic Details
Main Authors: Yi Xu, Weihong Jiang, Rui Wu, Siyu Zhang, Kaiwen Zhang, Haijing Xie, Haimeng Yin, Si Pan, Yumo Han, Bo You
Format: Article
Language:English
Published: BMJ Publishing Group 2025-02-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/2/e010301.full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items