Periorbital Silicone Granulomatosis 30 Years after Acupuncture

Silicone-based compounds are commonly used in many medical applications, such as coatings for needles and syringes. Foreign body granulomas are a well-recognized complication of silicone exposure; however, they may be challenging to identify without a clear history. A 61-year-old female patient with...

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Main Authors: Nathan Pirakitikulr, Ann Q. Tran, Armando L. Garcia, Sander R. Dubovy, Wendy W. Lee
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2020/6323646
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author Nathan Pirakitikulr
Ann Q. Tran
Armando L. Garcia
Sander R. Dubovy
Wendy W. Lee
author_facet Nathan Pirakitikulr
Ann Q. Tran
Armando L. Garcia
Sander R. Dubovy
Wendy W. Lee
author_sort Nathan Pirakitikulr
collection DOAJ
description Silicone-based compounds are commonly used in many medical applications, such as coatings for needles and syringes. Foreign body granulomas are a well-recognized complication of silicone exposure; however, they may be challenging to identify without a clear history. A 61-year-old female patient without prior history of periocular injections, filler, or surgery presented to our oculoplastic clinic with multiple periocular lesions. The patient subsequently underwent excisional biopsy of two prominent lesions, which were identified as granulomas on pathology. Further questioning revealed the cause to be facial acupuncture performed decades prior, and a subsequent targeted exam identified additional lesions at other needling sites. A third lesion was subsequently excised, and there was no recurrence at the last follow-up 3 months postsurgery. Acupuncture is an increasingly common but underrecognized source of silicone exposure and can present up to several decades after exposure as a chronic granulomatous response in a characteristic multifocal pattern.
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publishDate 2020-01-01
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-407124ae518a4e6fbef0d9e53ba0402b2025-02-03T00:58:44ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302020-01-01202010.1155/2020/63236466323646Periorbital Silicone Granulomatosis 30 Years after AcupunctureNathan Pirakitikulr0Ann Q. Tran1Armando L. Garcia2Sander R. Dubovy3Wendy W. Lee4Division of Oculofacial Plastic and Reconstructive Surgery, Bascom Palmer Eye Institute, University of Miami-Miller School of Medicine, Miami, FL, USADivision of Oculofacial Plastic and Reconstructive Surgery, Bascom Palmer Eye Institute, University of Miami-Miller School of Medicine, Miami, FL, USAFlorida Lions Ocular Pathology Laboratory, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USAFlorida Lions Ocular Pathology Laboratory, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USADivision of Oculofacial Plastic and Reconstructive Surgery, Bascom Palmer Eye Institute, University of Miami-Miller School of Medicine, Miami, FL, USASilicone-based compounds are commonly used in many medical applications, such as coatings for needles and syringes. Foreign body granulomas are a well-recognized complication of silicone exposure; however, they may be challenging to identify without a clear history. A 61-year-old female patient without prior history of periocular injections, filler, or surgery presented to our oculoplastic clinic with multiple periocular lesions. The patient subsequently underwent excisional biopsy of two prominent lesions, which were identified as granulomas on pathology. Further questioning revealed the cause to be facial acupuncture performed decades prior, and a subsequent targeted exam identified additional lesions at other needling sites. A third lesion was subsequently excised, and there was no recurrence at the last follow-up 3 months postsurgery. Acupuncture is an increasingly common but underrecognized source of silicone exposure and can present up to several decades after exposure as a chronic granulomatous response in a characteristic multifocal pattern.http://dx.doi.org/10.1155/2020/6323646
spellingShingle Nathan Pirakitikulr
Ann Q. Tran
Armando L. Garcia
Sander R. Dubovy
Wendy W. Lee
Periorbital Silicone Granulomatosis 30 Years after Acupuncture
Case Reports in Ophthalmological Medicine
title Periorbital Silicone Granulomatosis 30 Years after Acupuncture
title_full Periorbital Silicone Granulomatosis 30 Years after Acupuncture
title_fullStr Periorbital Silicone Granulomatosis 30 Years after Acupuncture
title_full_unstemmed Periorbital Silicone Granulomatosis 30 Years after Acupuncture
title_short Periorbital Silicone Granulomatosis 30 Years after Acupuncture
title_sort periorbital silicone granulomatosis 30 years after acupuncture
url http://dx.doi.org/10.1155/2020/6323646
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