Anesthesiological Management of a Patient with Williams Syndrome Undergoing Spine Surgery

Williams Syndrome (WS) is a complex neurodevelopmental disorder associated with a mutation on chromosome 7. Patients with WS usually display dysmorphic facial and musculoskeletal features, congenital heart diseases, metabolic disturbances and cognitive impairment. Structural cardiovascular abnormali...

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Main Authors: Federico Boncagni, Luca Pecora, Vasco Durazzi, Francesco Ventrella
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2016/1371095
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author Federico Boncagni
Luca Pecora
Vasco Durazzi
Francesco Ventrella
author_facet Federico Boncagni
Luca Pecora
Vasco Durazzi
Francesco Ventrella
author_sort Federico Boncagni
collection DOAJ
description Williams Syndrome (WS) is a complex neurodevelopmental disorder associated with a mutation on chromosome 7. Patients with WS usually display dysmorphic facial and musculoskeletal features, congenital heart diseases, metabolic disturbances and cognitive impairment. Structural cardiovascular abnormalities are present in the majority of the children and may provide a substrate for perioperative Sudden Cardiac Death, as presented by several reports, something that creates a great challenge to the anesthetic conduct. We present the case of a 12-year old girl who required anesthetic care for surgical correction of an acquired kyphoscoliosis. Potential anesthesiological implications of WS are subsequently reviewed.
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publishDate 2016-01-01
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series Case Reports in Anesthesiology
spelling doaj-art-4064db9ef52649f4bf249461aa9b68f02025-08-20T03:55:36ZengWileyCase Reports in Anesthesiology2090-63822090-63902016-01-01201610.1155/2016/13710951371095Anesthesiological Management of a Patient with Williams Syndrome Undergoing Spine SurgeryFederico Boncagni0Luca Pecora1Vasco Durazzi2Francesco Ventrella3Clinica di Rianimazione Generale, Respiratoria e del Trauma Maggiore, Azienda Ospedaliero-Universitaria “Ospedali Riuniti Umberto I-G. M. Lancisi-G. Salesi”, 60126 Ancona, ItalyAnestesia e Rianimazione dei Trapianti e della Chirurgia Maggiore, Azienda Ospedaliero-Universitaria “Ospedali Riuniti Umberto I-G. M. Lancisi-G. Salesi”, 60126 Ancona, ItalyClinica di Neurologia, Azienda Ospedaliero-Universitaria “Ospedali Riuniti Umberto I-G. M. Lancisi-G. Salesi”, 60126 Ancona, ItalyAnestesia e Rianimazione Pediatrica, Azienda Ospedaliero-Universitaria “Ospedali Riuniti Umberto I-G. M. Lancisi-G. Salesi”, 60126 Ancona, ItalyWilliams Syndrome (WS) is a complex neurodevelopmental disorder associated with a mutation on chromosome 7. Patients with WS usually display dysmorphic facial and musculoskeletal features, congenital heart diseases, metabolic disturbances and cognitive impairment. Structural cardiovascular abnormalities are present in the majority of the children and may provide a substrate for perioperative Sudden Cardiac Death, as presented by several reports, something that creates a great challenge to the anesthetic conduct. We present the case of a 12-year old girl who required anesthetic care for surgical correction of an acquired kyphoscoliosis. Potential anesthesiological implications of WS are subsequently reviewed.http://dx.doi.org/10.1155/2016/1371095
spellingShingle Federico Boncagni
Luca Pecora
Vasco Durazzi
Francesco Ventrella
Anesthesiological Management of a Patient with Williams Syndrome Undergoing Spine Surgery
Case Reports in Anesthesiology
title Anesthesiological Management of a Patient with Williams Syndrome Undergoing Spine Surgery
title_full Anesthesiological Management of a Patient with Williams Syndrome Undergoing Spine Surgery
title_fullStr Anesthesiological Management of a Patient with Williams Syndrome Undergoing Spine Surgery
title_full_unstemmed Anesthesiological Management of a Patient with Williams Syndrome Undergoing Spine Surgery
title_short Anesthesiological Management of a Patient with Williams Syndrome Undergoing Spine Surgery
title_sort anesthesiological management of a patient with williams syndrome undergoing spine surgery
url http://dx.doi.org/10.1155/2016/1371095
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