Balancing stability and function: impact of the surface charge of SARS-CoV-2 Omicron spike protein
Abstract The ectodomain of the Omicron SARS-CoV-2 spike has an increased positive surface charge, favoring binding to the host cell surface, but may affect the stability of the ectodomain. Thermal stability studies identified two transitions associated with the flexibility of the receptor binding do...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | npj Viruses |
| Online Access: | https://doi.org/10.1038/s44298-025-00104-1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|