FABP4 inhibition suppresses bone resorption and protects against postmenopausal osteoporosis in ovariectomized mice
Abstract Postmenopausal osteoporosis (PMOP) is a condition in women caused by estrogen deficiency, characterized by reduced bone mass and increased fracture risk. Fatty acid-binding protein 4 (FABP4), a lipid-binding protein involved in metabolism and inflammation, has emerged as a key regulator in...
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| Main Authors: | Qian Xie, Xiangfu Du, Jianhui Liang, Yanni Shen, Yufan Ling, Zhengji Huang, Zekai Ke, Tai Li, Bing Song, Tailin Wu, Yan Wang, Huiren Tao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-59719-w |
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