Chromosome-level genome assembly of the Phoxinus lagowskii

Abstract Phoxinus lagowskii is an economically important freshwater fish species native to China. In this study, a chromosome-level genome assembly of P. lagowskii was assembled using PacBio and Hi-C sequencing technologies. The total genome size was 1.22 Gb, with a contig N50 of 38.16 Mb. The final...

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Main Authors: Han Zheng, Peng Xie, Xiaoyu Zheng, Xufa Ma, Kaijian Wei, Rui Han
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-05779-y
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author Han Zheng
Peng Xie
Xiaoyu Zheng
Xufa Ma
Kaijian Wei
Rui Han
author_facet Han Zheng
Peng Xie
Xiaoyu Zheng
Xufa Ma
Kaijian Wei
Rui Han
author_sort Han Zheng
collection DOAJ
description Abstract Phoxinus lagowskii is an economically important freshwater fish species native to China. In this study, a chromosome-level genome assembly of P. lagowskii was assembled using PacBio and Hi-C sequencing technologies. The total genome size was 1.22 Gb, with a contig N50 of 38.16 Mb. The final assembly comprised 25 chromosomes, with an anchor rate of 96.29%, resulting in a total anchored length of 1,173,227,270 bp. The genome completeness, as evaluated by the BUSCO assessment, was 94.2%. The genome contained 33,449 predicted protein-coding genes, and the BUSCO completeness for the gene set was 93.6%. A total of 76,416 proteins were predicted, of which 95.29% had functional annotations. Repetitive sequences in the genome totaled 626.50 Mb, representing 51.42% of the entire genome. This genome assembly of P. lagowskii provides significant insights into its biological traits, genetic diversity, and adaptive responses to environmental pressures. Moreover, it lays the groundwork for future genetic improvements in the aquaculture of this species.
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issn 2052-4463
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spelling doaj-art-405de49914314365bc8530dbe0b9dc7e2025-08-20T04:01:47ZengNature PortfolioScientific Data2052-44632025-08-011211910.1038/s41597-025-05779-yChromosome-level genome assembly of the Phoxinus lagowskiiHan Zheng0Peng Xie1Xiaoyu Zheng2Xufa Ma3Kaijian Wei4Rui Han5College of Fisheries, Huazhong Agricultural UniversityHubei Key Laboratory of Edible Wild Plants Conservation and Utilization, College of Life Sciences, Hubei Normal UniversityCollege of Fisheries, Huazhong Agricultural UniversityCollege of Fisheries, Huazhong Agricultural UniversityCollege of Fisheries, Huazhong Agricultural UniversityState Key Loaboratory of Simulation and Regulation of Water Cycle in River Basin, China Institute of Water Resources and Hydropower ResearchAbstract Phoxinus lagowskii is an economically important freshwater fish species native to China. In this study, a chromosome-level genome assembly of P. lagowskii was assembled using PacBio and Hi-C sequencing technologies. The total genome size was 1.22 Gb, with a contig N50 of 38.16 Mb. The final assembly comprised 25 chromosomes, with an anchor rate of 96.29%, resulting in a total anchored length of 1,173,227,270 bp. The genome completeness, as evaluated by the BUSCO assessment, was 94.2%. The genome contained 33,449 predicted protein-coding genes, and the BUSCO completeness for the gene set was 93.6%. A total of 76,416 proteins were predicted, of which 95.29% had functional annotations. Repetitive sequences in the genome totaled 626.50 Mb, representing 51.42% of the entire genome. This genome assembly of P. lagowskii provides significant insights into its biological traits, genetic diversity, and adaptive responses to environmental pressures. Moreover, it lays the groundwork for future genetic improvements in the aquaculture of this species.https://doi.org/10.1038/s41597-025-05779-y
spellingShingle Han Zheng
Peng Xie
Xiaoyu Zheng
Xufa Ma
Kaijian Wei
Rui Han
Chromosome-level genome assembly of the Phoxinus lagowskii
Scientific Data
title Chromosome-level genome assembly of the Phoxinus lagowskii
title_full Chromosome-level genome assembly of the Phoxinus lagowskii
title_fullStr Chromosome-level genome assembly of the Phoxinus lagowskii
title_full_unstemmed Chromosome-level genome assembly of the Phoxinus lagowskii
title_short Chromosome-level genome assembly of the Phoxinus lagowskii
title_sort chromosome level genome assembly of the phoxinus lagowskii
url https://doi.org/10.1038/s41597-025-05779-y
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AT xufama chromosomelevelgenomeassemblyofthephoxinuslagowskii
AT kaijianwei chromosomelevelgenomeassemblyofthephoxinuslagowskii
AT ruihan chromosomelevelgenomeassemblyofthephoxinuslagowskii