Diet, Genetics, and Disease: A Focus on the Middle East and North Africa Region
The Middle East and North Africa (MENA) region suffers a drastic change from a traditional diet to an industrialized diet. This has led to an unparalleled increase in the prevalence of chronic diseases. This review discusses the role of nutritional genomics, or the dietary signature, in these dietar...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Nutrition and Metabolism |
| Online Access: | http://dx.doi.org/10.1155/2012/109037 |
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| author | Akl C. Fahed Abdul-Karim M. El-Hage-Sleiman Theresa I. Farhat Georges M. Nemer |
| author_facet | Akl C. Fahed Abdul-Karim M. El-Hage-Sleiman Theresa I. Farhat Georges M. Nemer |
| author_sort | Akl C. Fahed |
| collection | DOAJ |
| description | The Middle East and North Africa (MENA) region suffers a drastic change from a traditional diet to an industrialized diet. This has led to an unparalleled increase in the prevalence of chronic diseases. This review discusses the role of nutritional genomics, or the dietary signature, in these dietary and disease changes in the MENA. The diet-genetics-disease relation is discussed in detail. Selected disease categories in the MENA are discussed starting with a review of their epidemiology in the different MENA countries, followed by an examination of the known genetic factors that have been reported in the disease discussed, whether inside or outside the MENA. Several diet-genetics-disease relationships in the MENA may be contributing to the increased prevalence of civilization disorders of metabolism and micronutrient deficiencies. Future research in the field of nutritional genomics in the MENA is needed to better define these relationships. |
| format | Article |
| id | doaj-art-405712719cc3480a808d60b29b4eefac |
| institution | Kabale University |
| issn | 2090-0724 2090-0732 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nutrition and Metabolism |
| spelling | doaj-art-405712719cc3480a808d60b29b4eefac2025-08-20T03:55:36ZengWileyJournal of Nutrition and Metabolism2090-07242090-07322012-01-01201210.1155/2012/109037109037Diet, Genetics, and Disease: A Focus on the Middle East and North Africa RegionAkl C. Fahed0Abdul-Karim M. El-Hage-Sleiman1Theresa I. Farhat2Georges M. Nemer3Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USADepartment of Biochemistry and Molecular Genetics, American University of Beirut, Beirut 1107 2020, LebanonDepartment of Biochemistry and Molecular Genetics, American University of Beirut, Beirut 1107 2020, LebanonDepartment of Biochemistry and Molecular Genetics, American University of Beirut, Beirut 1107 2020, LebanonThe Middle East and North Africa (MENA) region suffers a drastic change from a traditional diet to an industrialized diet. This has led to an unparalleled increase in the prevalence of chronic diseases. This review discusses the role of nutritional genomics, or the dietary signature, in these dietary and disease changes in the MENA. The diet-genetics-disease relation is discussed in detail. Selected disease categories in the MENA are discussed starting with a review of their epidemiology in the different MENA countries, followed by an examination of the known genetic factors that have been reported in the disease discussed, whether inside or outside the MENA. Several diet-genetics-disease relationships in the MENA may be contributing to the increased prevalence of civilization disorders of metabolism and micronutrient deficiencies. Future research in the field of nutritional genomics in the MENA is needed to better define these relationships.http://dx.doi.org/10.1155/2012/109037 |
| spellingShingle | Akl C. Fahed Abdul-Karim M. El-Hage-Sleiman Theresa I. Farhat Georges M. Nemer Diet, Genetics, and Disease: A Focus on the Middle East and North Africa Region Journal of Nutrition and Metabolism |
| title | Diet, Genetics, and Disease: A Focus on the Middle East and North Africa Region |
| title_full | Diet, Genetics, and Disease: A Focus on the Middle East and North Africa Region |
| title_fullStr | Diet, Genetics, and Disease: A Focus on the Middle East and North Africa Region |
| title_full_unstemmed | Diet, Genetics, and Disease: A Focus on the Middle East and North Africa Region |
| title_short | Diet, Genetics, and Disease: A Focus on the Middle East and North Africa Region |
| title_sort | diet genetics and disease a focus on the middle east and north africa region |
| url | http://dx.doi.org/10.1155/2012/109037 |
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