Gluten-Associated Neurological Disorders: A Cases Series
Introduction: Gluten-associated disorders, including celiac disease (CeD) and non-celiac gluten sensitivity (NCGS), can present with various extraintestinal neurologic manifestations, including sensory neuropathy, ataxia, headaches, and seizures. Case Presentations: In this case series, w...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2025-05-01
|
| Series: | Case Reports in Gastroenterology |
| Online Access: | https://karger.com/article/doi/10.1159/000544765 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850231951566307328 |
|---|---|
| author | Vismaya S. Bachu Farinaz Ghodrati Brent L. Fogel Guy A. Weiss |
| author_facet | Vismaya S. Bachu Farinaz Ghodrati Brent L. Fogel Guy A. Weiss |
| author_sort | Vismaya S. Bachu |
| collection | DOAJ |
| description |
Introduction: Gluten-associated disorders, including celiac disease (CeD) and non-celiac gluten sensitivity (NCGS), can present with various extraintestinal neurologic manifestations, including sensory neuropathy, ataxia, headaches, and seizures. Case Presentations: In this case series, we present 3 interesting patients with gluten-associated neurological disorders (GAND) across a spectrum of gluten-associated disorders severity, from gluten sensitivity, to CeD, to refractory CeD, illustrating variable presentations and treatment approaches for this underdiagnosed population. Conclusion: For many patients with neurological presentations who initially lack gastrointestinal symptoms, diagnosis remains challenging. Once diagnosed, while a gluten-free diet has been the mainstay of treating GAND for many years, this approach may only prevent progression of disease without reversal of symptoms. Further studies are needed to help guide the development and standardization of treatments for this patient population. |
| format | Article |
| id | doaj-art-4055fc09e93041c6a772bdaba8f0e294 |
| institution | OA Journals |
| issn | 1662-0631 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj-art-4055fc09e93041c6a772bdaba8f0e2942025-08-20T02:03:20ZengKarger PublishersCase Reports in Gastroenterology1662-06312025-05-0119138739110.1159/000544765Gluten-Associated Neurological Disorders: A Cases SeriesVismaya S. BachuFarinaz GhodratiBrent L. FogelGuy A. Weiss Introduction: Gluten-associated disorders, including celiac disease (CeD) and non-celiac gluten sensitivity (NCGS), can present with various extraintestinal neurologic manifestations, including sensory neuropathy, ataxia, headaches, and seizures. Case Presentations: In this case series, we present 3 interesting patients with gluten-associated neurological disorders (GAND) across a spectrum of gluten-associated disorders severity, from gluten sensitivity, to CeD, to refractory CeD, illustrating variable presentations and treatment approaches for this underdiagnosed population. Conclusion: For many patients with neurological presentations who initially lack gastrointestinal symptoms, diagnosis remains challenging. Once diagnosed, while a gluten-free diet has been the mainstay of treating GAND for many years, this approach may only prevent progression of disease without reversal of symptoms. Further studies are needed to help guide the development and standardization of treatments for this patient population. https://karger.com/article/doi/10.1159/000544765 |
| spellingShingle | Vismaya S. Bachu Farinaz Ghodrati Brent L. Fogel Guy A. Weiss Gluten-Associated Neurological Disorders: A Cases Series Case Reports in Gastroenterology |
| title | Gluten-Associated Neurological Disorders: A Cases Series |
| title_full | Gluten-Associated Neurological Disorders: A Cases Series |
| title_fullStr | Gluten-Associated Neurological Disorders: A Cases Series |
| title_full_unstemmed | Gluten-Associated Neurological Disorders: A Cases Series |
| title_short | Gluten-Associated Neurological Disorders: A Cases Series |
| title_sort | gluten associated neurological disorders a cases series |
| url | https://karger.com/article/doi/10.1159/000544765 |
| work_keys_str_mv | AT vismayasbachu glutenassociatedneurologicaldisordersacasesseries AT farinazghodrati glutenassociatedneurologicaldisordersacasesseries AT brentlfogel glutenassociatedneurologicaldisordersacasesseries AT guyaweiss glutenassociatedneurologicaldisordersacasesseries |