Tomato arabinosyltransferase prevents precocious senescence

Senescence, a crucial developmental process in the life cycle of plants, involves programmed destruction of cellular components of leaves. The onset of senescence is synchronized with other developmental processes for successful reproduction since senescence eventually leads to cell death. Arabinosy...

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Main Authors: Ho-Young Jeong, Yoonseo Lim, Myeong-Gyun Seo, Soon Ju Park, Chanhui Lee, Young-Joon Park, Choon-Tak Kwon
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-07-01
Series:Horticultural Plant Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S2468014124000323
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author Ho-Young Jeong
Yoonseo Lim
Myeong-Gyun Seo
Soon Ju Park
Chanhui Lee
Young-Joon Park
Choon-Tak Kwon
author_facet Ho-Young Jeong
Yoonseo Lim
Myeong-Gyun Seo
Soon Ju Park
Chanhui Lee
Young-Joon Park
Choon-Tak Kwon
author_sort Ho-Young Jeong
collection DOAJ
description Senescence, a crucial developmental process in the life cycle of plants, involves programmed destruction of cellular components of leaves. The onset of senescence is synchronized with other developmental processes for successful reproduction since senescence eventually leads to cell death. Arabinosyltransferase FASCIATED AND BRANCHED 2 (FAB2) is known to control meristem proliferation. Here, we show that FAB2 could inhibit premature leaf senescence in tomato plants. Both chemically mutagenized and CRISPR-generated fab2 mutants exhibited excessively accelerated senescence, which resulted in sterility. Transcriptome analysis revealed that FAB2 extended leaf longevity by suppressing transcription of genes highly expressed in mature leaves. Transcription of FAB2 was increased in younger leaves, potentially inhibiting premature leaf senescence. The precocious senescence of fab2 mutants was in contrast to fasciated inflorescence (fin) mutants, which carried mutations in a hydroxyproline O-arabinosyltransferase gene, leading to meristem overproliferation. Our observations indicate that complex genetic hierarchy in the cascade of tomato arabinosyltransferases could control different aspects of developmental processes such as stem cell proliferation and senescence.
format Article
id doaj-art-4051a53cb2ca4d72b27cfe8207856cdb
institution Kabale University
issn 2468-0141
language English
publishDate 2025-07-01
publisher KeAi Communications Co., Ltd.
record_format Article
series Horticultural Plant Journal
spelling doaj-art-4051a53cb2ca4d72b27cfe8207856cdb2025-08-20T03:28:24ZengKeAi Communications Co., Ltd.Horticultural Plant Journal2468-01412025-07-011141583159410.1016/j.hpj.2023.11.006Tomato arabinosyltransferase prevents precocious senescenceHo-Young Jeong0Yoonseo Lim1Myeong-Gyun Seo2Soon Ju Park3Chanhui Lee4Young-Joon Park5Choon-Tak Kwon6Department of Plant & Environmental New Resources, Kyung Hee University, Yongin 17104, Republic of KoreaGraduate School of Green-Bio Science, Kyung Hee University, Yongin 17104, Republic of KoreaGraduate School of Green-Bio Science, Kyung Hee University, Yongin 17104, Republic of KoreaDivision of Applied Life Science, Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Gyeongsang National University, Jinju 52828, Republic of KoreaDepartment of Plant & Environmental New Resources, Kyung Hee University, Yongin 17104, Republic of Korea; Graduate School of Green-Bio Science, Kyung Hee University, Yongin 17104, Republic of KoreaDepartment of Smart Farm Science, Kyung Hee University, Yongin 17104, Republic of Korea; Corresponding authors.Graduate School of Green-Bio Science, Kyung Hee University, Yongin 17104, Republic of Korea; Department of Smart Farm Science, Kyung Hee University, Yongin 17104, Republic of Korea; Corresponding authors.Senescence, a crucial developmental process in the life cycle of plants, involves programmed destruction of cellular components of leaves. The onset of senescence is synchronized with other developmental processes for successful reproduction since senescence eventually leads to cell death. Arabinosyltransferase FASCIATED AND BRANCHED 2 (FAB2) is known to control meristem proliferation. Here, we show that FAB2 could inhibit premature leaf senescence in tomato plants. Both chemically mutagenized and CRISPR-generated fab2 mutants exhibited excessively accelerated senescence, which resulted in sterility. Transcriptome analysis revealed that FAB2 extended leaf longevity by suppressing transcription of genes highly expressed in mature leaves. Transcription of FAB2 was increased in younger leaves, potentially inhibiting premature leaf senescence. The precocious senescence of fab2 mutants was in contrast to fasciated inflorescence (fin) mutants, which carried mutations in a hydroxyproline O-arabinosyltransferase gene, leading to meristem overproliferation. Our observations indicate that complex genetic hierarchy in the cascade of tomato arabinosyltransferases could control different aspects of developmental processes such as stem cell proliferation and senescence.http://www.sciencedirect.com/science/article/pii/S2468014124000323ArabinosyltransferaseLeaf senescenceCRISPRFAB2Transcriptome analysis
spellingShingle Ho-Young Jeong
Yoonseo Lim
Myeong-Gyun Seo
Soon Ju Park
Chanhui Lee
Young-Joon Park
Choon-Tak Kwon
Tomato arabinosyltransferase prevents precocious senescence
Horticultural Plant Journal
Arabinosyltransferase
Leaf senescence
CRISPR
FAB2
Transcriptome analysis
title Tomato arabinosyltransferase prevents precocious senescence
title_full Tomato arabinosyltransferase prevents precocious senescence
title_fullStr Tomato arabinosyltransferase prevents precocious senescence
title_full_unstemmed Tomato arabinosyltransferase prevents precocious senescence
title_short Tomato arabinosyltransferase prevents precocious senescence
title_sort tomato arabinosyltransferase prevents precocious senescence
topic Arabinosyltransferase
Leaf senescence
CRISPR
FAB2
Transcriptome analysis
url http://www.sciencedirect.com/science/article/pii/S2468014124000323
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AT yoonseolim tomatoarabinosyltransferasepreventsprecocioussenescence
AT myeonggyunseo tomatoarabinosyltransferasepreventsprecocioussenescence
AT soonjupark tomatoarabinosyltransferasepreventsprecocioussenescence
AT chanhuilee tomatoarabinosyltransferasepreventsprecocioussenescence
AT youngjoonpark tomatoarabinosyltransferasepreventsprecocioussenescence
AT choontakkwon tomatoarabinosyltransferasepreventsprecocioussenescence