Avacopan Causing Vanishing Bile Duct Syndrome in an Adult Patient With Microscopic Polyangiitis

Avacopan Causing Vanishing Bile Duct Syndrome in an Adult Patient With Microscopic Polyangiitis

Microscopic polyangiitis (MPA) is a systemic necrotizing small-vessel vasculitis that may affect multiple organs. Avacopan, an oral complement (C5a) receptor inhibitor, was recently approved and recommended as a glucocorticoid-sparing induction therapy for severe granulomatosis with polyangiitis and...

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Main Authors: Alexander Tang, David M.P. Di Fonzo, Saba Alsaddah, Chelsea Maedler-Kron, Arielle Mendel, Giada Sebastiani
Format: Article
Language:English
Published: American College of Physicians 2024-11-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2024.0602
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