Oncolytic vaccinia virus harboring CLEC2A gene enhances viral replication and antitumor efficacy
In the field of innovative cancer treatment strategies, oncolytic vaccinia virus (VV)es have gained traction as promising vectors. In the current study, we inserted the human C-type lectin domain family 2 member A (CLEC2A) gene into VV, creating a replicating therapeutic, oncoVV-CLEC2A. The findings...
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Main Authors: | Chunqing Gao, Qi Ying, Yufeng Qiu, Ningbo Ren, Kan Chen, Yanrong Zhou, Ting Ye, Gongchu Li |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-09-01
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Series: | Molecular Therapy: Oncology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2950329924000651 |
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