Unlocking tiny titans: 360 view of the quantum dots nanotechnology for dental applications

Quantum dots (QDs) nanotechnology has gained significant attention in dentistry due to its unique properties, such as fluorescence, antimicrobial activity, and drug delivery potential. This review aims to identify the dental applications most actively incorporating QD technology and to examine the d...

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Main Authors: Tasneem Alluhaidan, Isadora Martini Garcia, Meghan Alexis, Masoumah Qaw, Fabrício Mezzomo Collares, Mary Ann Williams, Mary Anne S. Melo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Dental Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fdmed.2025.1503057/full
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author Tasneem Alluhaidan
Tasneem Alluhaidan
Isadora Martini Garcia
Meghan Alexis
Masoumah Qaw
Masoumah Qaw
Fabrício Mezzomo Collares
Mary Ann Williams
Mary Anne S. Melo
Mary Anne S. Melo
author_facet Tasneem Alluhaidan
Tasneem Alluhaidan
Isadora Martini Garcia
Meghan Alexis
Masoumah Qaw
Masoumah Qaw
Fabrício Mezzomo Collares
Mary Ann Williams
Mary Anne S. Melo
Mary Anne S. Melo
author_sort Tasneem Alluhaidan
collection DOAJ
description Quantum dots (QDs) nanotechnology has gained significant attention in dentistry due to its unique properties, such as fluorescence, antimicrobial activity, and drug delivery potential. This review aims to identify the dental applications most actively incorporating QD technology and to examine the distinctive properties of QDs within Dentistry. Employing the Arksey and O'Malley five-stage framework, a systematic search was conducted across PubMed, EMBASE, and Scopus databases for English-language publications on QDs in dentistry. Scientific contributions were evaluated by analyzing publication volume, research trends, patents, and key areas of investigation. Of the 1,034 studies initially identified, 71 were fully screened, with 22 meeting the criteria for data extraction. Results showed that antimicrobial properties and bone regeneration are the primary focus areas for QDs in dental materials. Stock solutions and resin composites are the most common materials developed, with the studies primarily targeting ofenhancing antimicrobial capabilities and osteogenesis enhancement. Over the last decade, QDs have demonstrated potential in enhancing drug delivery, antimicrobial efficacy, and optical performance in dental materials. Despite their growing prominence, the clinical translation of QD-based technologies remains limited due to a lack of long-term studies.
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spelling doaj-art-4040149e82a349dcbd9395b60a1bb5ae2025-08-20T03:15:48ZengFrontiers Media S.A.Frontiers in Dental Medicine2673-49152025-03-01610.3389/fdmed.2025.15030571503057Unlocking tiny titans: 360 view of the quantum dots nanotechnology for dental applicationsTasneem Alluhaidan0Tasneem Alluhaidan1Isadora Martini Garcia2Meghan Alexis3Masoumah Qaw4Masoumah Qaw5Fabrício Mezzomo Collares6Mary Ann Williams7Mary Anne S. Melo8Mary Anne S. Melo9Dental Biomedical Sciences Ph.D. Program, University of Maryland School of Dentistry, Baltimore, MD, United StatesDepartment of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi ArabiaDepartment of Comprehensive Dentistry, University of Maryland School of Dentistry, Baltimore, MD, United StatesDepartment of Comprehensive Dentistry, University of Maryland School of Dentistry, Baltimore, MD, United StatesDental Biomedical Sciences Ph.D. Program, University of Maryland School of Dentistry, Baltimore, MD, United StatesDepartment of Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi ArabiaDepartment of Dental Materials, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, BrazilHealth Sciences and Human Services Library, University of Maryland, Baltimore, MD, United StatesDental Biomedical Sciences Ph.D. Program, University of Maryland School of Dentistry, Baltimore, MD, United StatesDepartment of Comprehensive Dentistry, University of Maryland School of Dentistry, Baltimore, MD, United StatesQuantum dots (QDs) nanotechnology has gained significant attention in dentistry due to its unique properties, such as fluorescence, antimicrobial activity, and drug delivery potential. This review aims to identify the dental applications most actively incorporating QD technology and to examine the distinctive properties of QDs within Dentistry. Employing the Arksey and O'Malley five-stage framework, a systematic search was conducted across PubMed, EMBASE, and Scopus databases for English-language publications on QDs in dentistry. Scientific contributions were evaluated by analyzing publication volume, research trends, patents, and key areas of investigation. Of the 1,034 studies initially identified, 71 were fully screened, with 22 meeting the criteria for data extraction. Results showed that antimicrobial properties and bone regeneration are the primary focus areas for QDs in dental materials. Stock solutions and resin composites are the most common materials developed, with the studies primarily targeting ofenhancing antimicrobial capabilities and osteogenesis enhancement. Over the last decade, QDs have demonstrated potential in enhancing drug delivery, antimicrobial efficacy, and optical performance in dental materials. Despite their growing prominence, the clinical translation of QD-based technologies remains limited due to a lack of long-term studies.https://www.frontiersin.org/articles/10.3389/fdmed.2025.1503057/fullnanoparticlesnanotechnologydental cariesdrug deliverydental materials
spellingShingle Tasneem Alluhaidan
Tasneem Alluhaidan
Isadora Martini Garcia
Meghan Alexis
Masoumah Qaw
Masoumah Qaw
Fabrício Mezzomo Collares
Mary Ann Williams
Mary Anne S. Melo
Mary Anne S. Melo
Unlocking tiny titans: 360 view of the quantum dots nanotechnology for dental applications
Frontiers in Dental Medicine
nanoparticles
nanotechnology
dental caries
drug delivery
dental materials
title Unlocking tiny titans: 360 view of the quantum dots nanotechnology for dental applications
title_full Unlocking tiny titans: 360 view of the quantum dots nanotechnology for dental applications
title_fullStr Unlocking tiny titans: 360 view of the quantum dots nanotechnology for dental applications
title_full_unstemmed Unlocking tiny titans: 360 view of the quantum dots nanotechnology for dental applications
title_short Unlocking tiny titans: 360 view of the quantum dots nanotechnology for dental applications
title_sort unlocking tiny titans 360 view of the quantum dots nanotechnology for dental applications
topic nanoparticles
nanotechnology
dental caries
drug delivery
dental materials
url https://www.frontiersin.org/articles/10.3389/fdmed.2025.1503057/full
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