Overcoming photon and spatiotemporal sparsity in fluorescence lifetime imaging with SparseFLIM

Overcoming photon and spatiotemporal sparsity in fluorescence lifetime imaging with SparseFLIM

Abstract Fluorescence lifetime imaging microscopy (FLIM) provides quantitative readouts of biochemical microenvironments, holding great promise for biomedical imaging. However, conventional FLIM relies on slow photon counting routines to accumulate sufficient photon statistics, restricting acquisiti...

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Bibliographic Details
Main Authors:	Binglin Shen, Yuan Lu, Fangyin Guo, Fangrui Lin, Rui Hu, Feng Rao, Junle Qu, Liwei Liu
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-10-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-024-07080-x
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