SPATS2L is a positive feedback regulator of the type I interferon signaling pathway and plays a vital role in lupus

SPATS2L is a positive feedback regulator of the type I interferon signaling pathway and plays a vital role in lupus

Through genome-wide association studies (GWAS) and integrated expression quantitative trait locus (eQTL) analyses, numerous susceptibility genes (“eGenes”, whose expressions are significantly associated with common variants) associated with systemic lupus erythematosus (SLE) have been identified. No...

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Main Authors: Chen Mengke, Zhang Yutong, Shi Weiwen, Song Xuejiao, Yang Yue, Hou Guojun, Ding Huihua, Chen Sheng, Yang Wanling, Shen Nan, Cui Yong, Zuo Xianbo, Tang Yuanjia
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-08-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
systemic lupus erythematosus
SPATS2L
quantitative trait loci
type I interferon
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024132
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