Early breast cancer detection in CT scans using convolutional neural bidirectional feature pyramid network

Breast cancer is one of the leading causes of death among women worldwide. Early detection plays a crucial role in reducing mortality rates. While mammography is a widely used diagnostic tool, computed tomography (CT) scans are increasingly being explored for detecting breast cancer due to their hig...

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Main Authors: Tahani Jaser Alahmadi, Adeel Ahmed, Amjad Rehman, Abeer Rashad Mirdad, Bayan Al Ghofaily, Shehryar Ali
Format: Article
Language:English
Published: PeerJ Inc. 2025-07-01
Series:PeerJ Computer Science
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Online Access:https://peerj.com/articles/cs-2994.pdf
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author Tahani Jaser Alahmadi
Adeel Ahmed
Amjad Rehman
Abeer Rashad Mirdad
Bayan Al Ghofaily
Shehryar Ali
author_facet Tahani Jaser Alahmadi
Adeel Ahmed
Amjad Rehman
Abeer Rashad Mirdad
Bayan Al Ghofaily
Shehryar Ali
author_sort Tahani Jaser Alahmadi
collection DOAJ
description Breast cancer is one of the leading causes of death among women worldwide. Early detection plays a crucial role in reducing mortality rates. While mammography is a widely used diagnostic tool, computed tomography (CT) scans are increasingly being explored for detecting breast cancer due to their high-resolution imaging and ability to visualize tissue in 3D. Despite the potential of CT scans in visualizing breast tissue in 3D with high resolution, extracting meaningful patterns from these scans is difficult due to the complex and nonlinear nature of the tissue features. The challenge lies in developing computational methods that can accurately detect and localize breast cancer lesions, especially when the tumors vary in size, shape, and density. In this article, we proposed a framework called convolutional neural bidirectional feature pyramid network, which integrates multi-scale feature extraction and bidirectional feature fusion for breast cancer detection in CT scans. The proposed framework classified the images into diseased and non-diseased and then identified the infected region on breast tissue. Using convolutional neural networks, we defined several layers to classify the diseased and normal CT scan images. We collected data on breast CT scans taken from the radiology department, Ayub Teaching Hospital Abbottabad, Pakistan. We evaluated the model using a variety of classification metrics such as precision, recall, F1-measure, and average precision to determine its effectiveness in finding breast cancer lesions, and we found 96.11% accuracy. Our findings show that compared with current state-of-the-art methods, the proposed framework has satisfactory results in identifying breast cancer areas, and the proposed framework over the baselines has achieved a 1.71% improvement.
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spelling doaj-art-401d073232764a2ca66e7eb3f7bd41e02025-08-20T03:31:37ZengPeerJ Inc.PeerJ Computer Science2376-59922025-07-0111e299410.7717/peerj-cs.2994Early breast cancer detection in CT scans using convolutional neural bidirectional feature pyramid networkTahani Jaser Alahmadi0Adeel Ahmed1Amjad Rehman2Abeer Rashad Mirdad3Bayan Al Ghofaily4Shehryar Ali5Department of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaDepartment of Information Technology, The University of Haripur, Haripur, PakistanArtificial Intelligence & Data Analytics Lab (AIDA) CCIS, Prince Sultan University, Riyadh, Saudi ArabiaArtificial Intelligence & Data Analytics Lab (AIDA) CCIS, Prince Sultan University, Riyadh, Saudi ArabiaArtificial Intelligence & Data Analytics Lab (AIDA) CCIS, Prince Sultan University, Riyadh, Saudi ArabiaDepartment of Information Technology, The University of Haripur, Haripur, PakistanBreast cancer is one of the leading causes of death among women worldwide. Early detection plays a crucial role in reducing mortality rates. While mammography is a widely used diagnostic tool, computed tomography (CT) scans are increasingly being explored for detecting breast cancer due to their high-resolution imaging and ability to visualize tissue in 3D. Despite the potential of CT scans in visualizing breast tissue in 3D with high resolution, extracting meaningful patterns from these scans is difficult due to the complex and nonlinear nature of the tissue features. The challenge lies in developing computational methods that can accurately detect and localize breast cancer lesions, especially when the tumors vary in size, shape, and density. In this article, we proposed a framework called convolutional neural bidirectional feature pyramid network, which integrates multi-scale feature extraction and bidirectional feature fusion for breast cancer detection in CT scans. The proposed framework classified the images into diseased and non-diseased and then identified the infected region on breast tissue. Using convolutional neural networks, we defined several layers to classify the diseased and normal CT scan images. We collected data on breast CT scans taken from the radiology department, Ayub Teaching Hospital Abbottabad, Pakistan. We evaluated the model using a variety of classification metrics such as precision, recall, F1-measure, and average precision to determine its effectiveness in finding breast cancer lesions, and we found 96.11% accuracy. Our findings show that compared with current state-of-the-art methods, the proposed framework has satisfactory results in identifying breast cancer areas, and the proposed framework over the baselines has achieved a 1.71% improvement.https://peerj.com/articles/cs-2994.pdfConvolutional neural networkBreast cancerComputed tomographyBidirectional feature pyramid networkMulti-scale featuresTumor localization
spellingShingle Tahani Jaser Alahmadi
Adeel Ahmed
Amjad Rehman
Abeer Rashad Mirdad
Bayan Al Ghofaily
Shehryar Ali
Early breast cancer detection in CT scans using convolutional neural bidirectional feature pyramid network
PeerJ Computer Science
Convolutional neural network
Breast cancer
Computed tomography
Bidirectional feature pyramid network
Multi-scale features
Tumor localization
title Early breast cancer detection in CT scans using convolutional neural bidirectional feature pyramid network
title_full Early breast cancer detection in CT scans using convolutional neural bidirectional feature pyramid network
title_fullStr Early breast cancer detection in CT scans using convolutional neural bidirectional feature pyramid network
title_full_unstemmed Early breast cancer detection in CT scans using convolutional neural bidirectional feature pyramid network
title_short Early breast cancer detection in CT scans using convolutional neural bidirectional feature pyramid network
title_sort early breast cancer detection in ct scans using convolutional neural bidirectional feature pyramid network
topic Convolutional neural network
Breast cancer
Computed tomography
Bidirectional feature pyramid network
Multi-scale features
Tumor localization
url https://peerj.com/articles/cs-2994.pdf
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