Assessment of anterior scleral thickness in Turkish open angle glaucoma patients: an anterior segment optical coherence tomography study
Abstract Background To compare anterior scleral thickness (AST) in Turkish patients with open-angle glaucoma (primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEG)) with healthy controls. Methods This prospective study involved 41 patients with PEG, 69 patients with POAG, and 46 he...
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BMC
2025-02-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-025-03921-3 |
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| author | Işıl Merve Torun Melike Saridoğan |
| author_facet | Işıl Merve Torun Melike Saridoğan |
| author_sort | Işıl Merve Torun |
| collection | DOAJ |
| description | Abstract Background To compare anterior scleral thickness (AST) in Turkish patients with open-angle glaucoma (primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEG)) with healthy controls. Methods This prospective study involved 41 patients with PEG, 69 patients with POAG, and 46 healthy controls. We obtained spectral domain anterior segment optical coherence tomography (AS-OCT) images from the nasal and temporal quadrants and made AST measurements of 1 mm (AST), 2 mm (AST2), 3 mm (AST3), and 4 mm (AST4) posterior to the scleral spur (SS). Schlemm's canal (SC) diameter and area measurements were performed using the ImageJ software. The results were compared statistically. Results The average ASTs of the groups did not differ significantly (p > 0.05 for each). The analysis of the nasal SC diameter revealed a significant decrease in the POAG group in comparison with the PEG group, with no difference observed between the POAG and control groups (p = 0.038*). The mean nasal and temporal SC area was significantly smaller in the PEG and POAG groups compared with the control group (p < 0.001** and p < 0.001**, respectively). Conclusions There was no significant difference in nasal and temporal AST between groups; however, the SC area was found to be smaller in glaucoma groups compared with healthy controls. The present findings should be supported by further studies. |
| format | Article |
| id | doaj-art-401cf4d7469d47ca9487009580c6c1cd |
| institution | DOAJ |
| issn | 1471-2415 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
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| series | BMC Ophthalmology |
| spelling | doaj-art-401cf4d7469d47ca9487009580c6c1cd2025-08-20T03:10:53ZengBMCBMC Ophthalmology1471-24152025-02-012511810.1186/s12886-025-03921-3Assessment of anterior scleral thickness in Turkish open angle glaucoma patients: an anterior segment optical coherence tomography studyIşıl Merve Torun0Melike Saridoğan1Department of Ophthalmology, Medical Health Sciences University, Sultan Abdülhamid Han Training and Research HospitalDepartment of Ophthalmology, Medical Health Sciences University, Sultan Abdülhamid Han Training and Research HospitalAbstract Background To compare anterior scleral thickness (AST) in Turkish patients with open-angle glaucoma (primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEG)) with healthy controls. Methods This prospective study involved 41 patients with PEG, 69 patients with POAG, and 46 healthy controls. We obtained spectral domain anterior segment optical coherence tomography (AS-OCT) images from the nasal and temporal quadrants and made AST measurements of 1 mm (AST), 2 mm (AST2), 3 mm (AST3), and 4 mm (AST4) posterior to the scleral spur (SS). Schlemm's canal (SC) diameter and area measurements were performed using the ImageJ software. The results were compared statistically. Results The average ASTs of the groups did not differ significantly (p > 0.05 for each). The analysis of the nasal SC diameter revealed a significant decrease in the POAG group in comparison with the PEG group, with no difference observed between the POAG and control groups (p = 0.038*). The mean nasal and temporal SC area was significantly smaller in the PEG and POAG groups compared with the control group (p < 0.001** and p < 0.001**, respectively). Conclusions There was no significant difference in nasal and temporal AST between groups; however, the SC area was found to be smaller in glaucoma groups compared with healthy controls. The present findings should be supported by further studies.https://doi.org/10.1186/s12886-025-03921-3Anterior scleral thicknessAnterior segment optical coherence tomographyPrimary open-angle glaucomaPseudoexfoliation glaucomaSchlemm’s canal |
| spellingShingle | Işıl Merve Torun Melike Saridoğan Assessment of anterior scleral thickness in Turkish open angle glaucoma patients: an anterior segment optical coherence tomography study BMC Ophthalmology Anterior scleral thickness Anterior segment optical coherence tomography Primary open-angle glaucoma Pseudoexfoliation glaucoma Schlemm’s canal |
| title | Assessment of anterior scleral thickness in Turkish open angle glaucoma patients: an anterior segment optical coherence tomography study |
| title_full | Assessment of anterior scleral thickness in Turkish open angle glaucoma patients: an anterior segment optical coherence tomography study |
| title_fullStr | Assessment of anterior scleral thickness in Turkish open angle glaucoma patients: an anterior segment optical coherence tomography study |
| title_full_unstemmed | Assessment of anterior scleral thickness in Turkish open angle glaucoma patients: an anterior segment optical coherence tomography study |
| title_short | Assessment of anterior scleral thickness in Turkish open angle glaucoma patients: an anterior segment optical coherence tomography study |
| title_sort | assessment of anterior scleral thickness in turkish open angle glaucoma patients an anterior segment optical coherence tomography study |
| topic | Anterior scleral thickness Anterior segment optical coherence tomography Primary open-angle glaucoma Pseudoexfoliation glaucoma Schlemm’s canal |
| url | https://doi.org/10.1186/s12886-025-03921-3 |
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