Unraveling Ginsenoside Rg1’s osteoprotective pathways in zebrafish models of glucocorticoid induced osteoporosis via transcriptomics
Abstract In this study, the effects of Ginsenoside Rg1 (Rg1), the primary bioactive constituent of Panax ginseng roots, on glucocorticoid-induced osteoporosis (GIOP) were examined using a zebrafish model, with a focus on elucidating its underlying mechanisms. Our findings demonstrated that Rg1 treat...
Saved in:
| Main Authors: | Xinyu Fan, Ying Zhang, Xinyu Li, Junhui Ding, Jiaolong Huang, Kai Lian, Peng Duan, Chunhui Hu, Junchang Xu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-15284-2 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Zebrafish models for glucocorticoid-induced osteoporosis
by: Wen-Ying Lin, et al.
Published: (2022-01-01) -
Ginsenoside Rg1: A bioactive therapeutic agent for diverse liver diseases
by: Mingyu Wu, et al.
Published: (2025-02-01) -
Ginsenoside Rg1 inhibits angiogenesis in diabetic retinopathy through the miR‐100‐3p/FBXW7/c‐MYC molecular axis
by: Liping Xue, et al.
Published: (2025-05-01) -
Ginsenoside Rg3 Adjunctively Increases the Efficacy of Gefitinib Against NSCLC by Regulating EGFR Copy Number
by: Xinyi Lv, et al.
Published: (2025-07-01) -
Pharmacological mechanisms and drug delivery systems of ginsenoside Rg3: A comprehensive review
by: Zhong-Wei Yao, et al.
Published: (2025-06-01)