Evaluation of the influence of polymorphisms of the transporter genes (<i>RFC1</i>, <i>MDR1</i>) and <i>GGH</i> on the efficacy of methotrexate in rheumatoid arthritis

Evaluation of the influence of polymorphisms of the transporter genes (<i>RFC1</i>, <i>MDR1</i>) and <i>GGH</i> on the efficacy of methotrexate in rheumatoid arthritis

The efficacy of methotrexate (MT) in patients with rheumatoid arthritis (RA) may be determined by genetic factors.Objective: to evaluate the isolated and combined effects of single nucleotide polymorphisms (SNPs) of membrane transporter proteins (RFC1 80G>A and MDR1 3435C>T) and the GG...

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Main Authors:	I. V. Devald, E. A. Hodus, D. Yu. Nokhrin, E. B. Khromova, G. L. Ignatova, D. S. Stashkevich, A. M. Lila, A. L. Burmistrova
Format:	Article
Language:	Russian
Published:	IMA-PRESS LLC 2023-08-01
Series:	Современная ревматология
Subjects:	rheumatoid arthritis methotrexate efficacy transporter proteins gamma-glutamyl hydrolase
Online Access:	https://mrj.ima-press.net/mrj/article/view/1456
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