The effect of povidone-iodine 10% plus levofloxacin 0.5% before cataract surgery: a randomized clinical trial
Abstract This study was designed to assess the efficacy of using povidone-iodine (PVI) 10% and levofloxacin 0.5% about one hour before cataract surgery in minimizing aqueous contamination compared with using PVI 10%. The intervention group received three drops of mixed povidone-iodine and levofloxac...
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BMC
2025-03-01
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| Series: | BMC Research Notes |
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| Online Access: | https://doi.org/10.1186/s13104-025-07116-3 |
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| author | Ali Azimi Mohammad Reza Jafari Ehsan Namvar Nasrin Masihpour Shadi Meshksar |
| author_facet | Ali Azimi Mohammad Reza Jafari Ehsan Namvar Nasrin Masihpour Shadi Meshksar |
| author_sort | Ali Azimi |
| collection | DOAJ |
| description | Abstract This study was designed to assess the efficacy of using povidone-iodine (PVI) 10% and levofloxacin 0.5% about one hour before cataract surgery in minimizing aqueous contamination compared with using PVI 10%. The intervention group received three drops of mixed povidone-iodine and levofloxacin (PVI/Levofloxacin) solution one hour before surgery. After making the corneal incision in cataract surgery, 0.1 cc aqueous humor sample was taken and sent for culture. We compared the intervention group and control group using t-test and chi-square test in SPSS 25(Chicago IL, USA). 147 eyes of 147 patients were analyzed. The intervention and control groups consisted of 72 and 75 patients, respectively. The Control group showed significantly more positive cultures (16 cultures: 22.2%). the intervention group had four positive cultures (5.3%). (P-value = 0.005). Topical levofloxacin 0.5% and povidone-iodine 10% mixture showed promising results in reducing the number of bacteria in the aqueous humor. |
| format | Article |
| id | doaj-art-3fff9db4ec564864b7acd4c6a2956d5a |
| institution | DOAJ |
| issn | 1756-0500 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | BMC |
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| series | BMC Research Notes |
| spelling | doaj-art-3fff9db4ec564864b7acd4c6a2956d5a2025-08-20T02:51:24ZengBMCBMC Research Notes1756-05002025-03-011811510.1186/s13104-025-07116-3The effect of povidone-iodine 10% plus levofloxacin 0.5% before cataract surgery: a randomized clinical trialAli Azimi0Mohammad Reza Jafari1Ehsan Namvar2Nasrin Masihpour3Shadi Meshksar4Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical SciencesShiraz University of Medical SciencesPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical SciencesAhvaz Jundishapur University of Medical SciencesShiraz University of Medical SciencesAbstract This study was designed to assess the efficacy of using povidone-iodine (PVI) 10% and levofloxacin 0.5% about one hour before cataract surgery in minimizing aqueous contamination compared with using PVI 10%. The intervention group received three drops of mixed povidone-iodine and levofloxacin (PVI/Levofloxacin) solution one hour before surgery. After making the corneal incision in cataract surgery, 0.1 cc aqueous humor sample was taken and sent for culture. We compared the intervention group and control group using t-test and chi-square test in SPSS 25(Chicago IL, USA). 147 eyes of 147 patients were analyzed. The intervention and control groups consisted of 72 and 75 patients, respectively. The Control group showed significantly more positive cultures (16 cultures: 22.2%). the intervention group had four positive cultures (5.3%). (P-value = 0.005). Topical levofloxacin 0.5% and povidone-iodine 10% mixture showed promising results in reducing the number of bacteria in the aqueous humor.https://doi.org/10.1186/s13104-025-07116-3Povidone-iodineLevofloxacinEndophthalmitis |
| spellingShingle | Ali Azimi Mohammad Reza Jafari Ehsan Namvar Nasrin Masihpour Shadi Meshksar The effect of povidone-iodine 10% plus levofloxacin 0.5% before cataract surgery: a randomized clinical trial BMC Research Notes Povidone-iodine Levofloxacin Endophthalmitis |
| title | The effect of povidone-iodine 10% plus levofloxacin 0.5% before cataract surgery: a randomized clinical trial |
| title_full | The effect of povidone-iodine 10% plus levofloxacin 0.5% before cataract surgery: a randomized clinical trial |
| title_fullStr | The effect of povidone-iodine 10% plus levofloxacin 0.5% before cataract surgery: a randomized clinical trial |
| title_full_unstemmed | The effect of povidone-iodine 10% plus levofloxacin 0.5% before cataract surgery: a randomized clinical trial |
| title_short | The effect of povidone-iodine 10% plus levofloxacin 0.5% before cataract surgery: a randomized clinical trial |
| title_sort | effect of povidone iodine 10 plus levofloxacin 0 5 before cataract surgery a randomized clinical trial |
| topic | Povidone-iodine Levofloxacin Endophthalmitis |
| url | https://doi.org/10.1186/s13104-025-07116-3 |
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