Albumin for patients with acute large-vessel occlusive stroke undergoing endovascular therapy (ARISE): the protocol of a randomized double-blind trial

Albumin for patients with acute large-vessel occlusive stroke undergoing endovascular therapy (ARISE): the protocol of a randomized double-blind trial

BackgroundAlbumin is a multifunctional plasma protein that is mainly synthesized in the liver and may play a neuroprotective role in treating acute ischemic stroke (AIS). The efficacy of albumin in patients with AIS receiving reperfusion therapy remains unknown.MethodsARISE is a multicenter, randomi...

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Main Authors: Yuanyuan Liu, Xiao Dong, Xuehong Chu, Zhengfei Ma, Tingyu Yi, Changming Wen, Yifeng Liu, Jun Sun, Jing Xu, Wenbo Li, Lei Yang, Benxiao Wang, Lei Shi, Jianqiao Li, Xiaoman Zhang, Chaoqun Li, Wenhuo Chen, Chuanhui Li, Di Wu, Chengbei Hou, Chen Zhou, Ming Li, Yi Xu, Chuanjie Wu, Xunming Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Neurology
Subjects:
albumin
neuroprotection
endovascular therapy
acute ischemic stroke
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1570184/full
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