Dosimetric analysis of ultrasound-guided high intensity focused ultrasound ablation for breast fibroadenomas: a retrospective study
Objective To investigate the factors influencing the sonication dosage and efficiency of ultrasound-guided high intensity focused ultrasound (USgHIFU) for breast fibroadenomas.Materials and Methods Forty-nine patients with 78 breast fibroadenomas who underwent USgHIFU were retrospectively analyzed....
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2022.2074151 |
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| author | Cai Zhang Mengdi Liang Tiansong Xia Heng Yin Hongwei Yang Zhibiao Wang Lian Zhang |
| author_facet | Cai Zhang Mengdi Liang Tiansong Xia Heng Yin Hongwei Yang Zhibiao Wang Lian Zhang |
| author_sort | Cai Zhang |
| collection | DOAJ |
| description | Objective To investigate the factors influencing the sonication dosage and efficiency of ultrasound-guided high intensity focused ultrasound (USgHIFU) for breast fibroadenomas.Materials and Methods Forty-nine patients with 78 breast fibroadenomas who underwent USgHIFU were retrospectively analyzed. The energy efficiency factor (EEF) was set as dependent variable, and the factors possibly influencing the sonication dosage, including age, body mass index (BMI), fibroadenoma size, distance from the shallow margin of the fibroadenoma to skin, distance from the deep margin of the fibroadenoma to pectoralis major, types of near field acoustic pathway, and Adler blood flow classification of ultrasound, were set as independent variables. The correlation between EEF and these independent variables were analyzed, and an optimal scaling regression model was established.Results Fibroadenoma size, distance from the shallow margin of the fibroadenoma to skin and type of near field acoustic pathway had significant correlation with EEF (p < 0.05). An EEF (ŷ) dosimetry model of ŷ= −0.496X1 + 0.287X2 + 0.203X3 was established, in which X1 stands for size of fibroadenoma, X2 stands for the distance from shallow margin of the fibroadenoma to skin, and X3 stands for type of near field acoustic pathway. The predicted EEF value was significantly related to actual EEF (R = 0.698, p = 0.000).Conclusions Fibroadenoma size, distance from the shallow margin of the fibroadenoma to skin and type of near field acoustic pathway could be used as predictors to evaluate the dosage delivery of USgHIFU treatment for breast fibroadenomas. |
| format | Article |
| id | doaj-art-3ffe5016c2cb4b82b813f92bc789a571 |
| institution | Kabale University |
| issn | 0265-6736 1464-5157 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj-art-3ffe5016c2cb4b82b813f92bc789a5712025-08-20T03:51:24ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572022-12-0139174375010.1080/02656736.2022.2074151Dosimetric analysis of ultrasound-guided high intensity focused ultrasound ablation for breast fibroadenomas: a retrospective studyCai Zhang0Mengdi Liang1Tiansong Xia2Heng Yin3Hongwei Yang4Zhibiao Wang5Lian Zhang6College of Biomedical Engineering, Chongqing Medical University, Chongqing, ChinaDepartment of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, ChinaDepartment of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, ChinaSuining Central Hospital, Suining, ChinaSuining Central Hospital, Suining, ChinaState Key Laboratory of Ultrasound Engineering in Medicine, College of Biomedical Engineering, Chongqing Medical University, Chongqing, ChinaCollege of Biomedical Engineering, Chongqing Medical University, Chongqing, ChinaObjective To investigate the factors influencing the sonication dosage and efficiency of ultrasound-guided high intensity focused ultrasound (USgHIFU) for breast fibroadenomas.Materials and Methods Forty-nine patients with 78 breast fibroadenomas who underwent USgHIFU were retrospectively analyzed. The energy efficiency factor (EEF) was set as dependent variable, and the factors possibly influencing the sonication dosage, including age, body mass index (BMI), fibroadenoma size, distance from the shallow margin of the fibroadenoma to skin, distance from the deep margin of the fibroadenoma to pectoralis major, types of near field acoustic pathway, and Adler blood flow classification of ultrasound, were set as independent variables. The correlation between EEF and these independent variables were analyzed, and an optimal scaling regression model was established.Results Fibroadenoma size, distance from the shallow margin of the fibroadenoma to skin and type of near field acoustic pathway had significant correlation with EEF (p < 0.05). An EEF (ŷ) dosimetry model of ŷ= −0.496X1 + 0.287X2 + 0.203X3 was established, in which X1 stands for size of fibroadenoma, X2 stands for the distance from shallow margin of the fibroadenoma to skin, and X3 stands for type of near field acoustic pathway. The predicted EEF value was significantly related to actual EEF (R = 0.698, p = 0.000).Conclusions Fibroadenoma size, distance from the shallow margin of the fibroadenoma to skin and type of near field acoustic pathway could be used as predictors to evaluate the dosage delivery of USgHIFU treatment for breast fibroadenomas.https://www.tandfonline.com/doi/10.1080/02656736.2022.2074151High intensity focused ultrasoundbreast fibroadenomaenergy efficiency factordosage deliveryacoustic pathway |
| spellingShingle | Cai Zhang Mengdi Liang Tiansong Xia Heng Yin Hongwei Yang Zhibiao Wang Lian Zhang Dosimetric analysis of ultrasound-guided high intensity focused ultrasound ablation for breast fibroadenomas: a retrospective study International Journal of Hyperthermia High intensity focused ultrasound breast fibroadenoma energy efficiency factor dosage delivery acoustic pathway |
| title | Dosimetric analysis of ultrasound-guided high intensity focused ultrasound ablation for breast fibroadenomas: a retrospective study |
| title_full | Dosimetric analysis of ultrasound-guided high intensity focused ultrasound ablation for breast fibroadenomas: a retrospective study |
| title_fullStr | Dosimetric analysis of ultrasound-guided high intensity focused ultrasound ablation for breast fibroadenomas: a retrospective study |
| title_full_unstemmed | Dosimetric analysis of ultrasound-guided high intensity focused ultrasound ablation for breast fibroadenomas: a retrospective study |
| title_short | Dosimetric analysis of ultrasound-guided high intensity focused ultrasound ablation for breast fibroadenomas: a retrospective study |
| title_sort | dosimetric analysis of ultrasound guided high intensity focused ultrasound ablation for breast fibroadenomas a retrospective study |
| topic | High intensity focused ultrasound breast fibroadenoma energy efficiency factor dosage delivery acoustic pathway |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2022.2074151 |
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