Recent advances in the application of microbiota transplantation in chickens

Abstract Extensive evidence demonstrates that a healthy and well-balanced gut microbiota profoundly influences host nutrient absorption, immunity, and metabolism. Unlike mammals, early microbiota colonization in commercial poultry largely depends on the environment as chicks hatch in incubators unde...

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Main Authors: Haoran Zhao, Luke Comer, Muhammad Zeeshan Akram, Matthias Corion, Yang Li, Nadia Everaert
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Online Access:https://doi.org/10.1186/s40104-025-01233-6
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author Haoran Zhao
Luke Comer
Muhammad Zeeshan Akram
Matthias Corion
Yang Li
Nadia Everaert
author_facet Haoran Zhao
Luke Comer
Muhammad Zeeshan Akram
Matthias Corion
Yang Li
Nadia Everaert
author_sort Haoran Zhao
collection DOAJ
description Abstract Extensive evidence demonstrates that a healthy and well-balanced gut microbiota profoundly influences host nutrient absorption, immunity, and metabolism. Unlike mammals, early microbiota colonization in commercial poultry largely depends on the environment as chicks hatch in incubators under a relatively sterile environment (egg and incubator sterilization) without maternal-offspring interaction. The early gut microbiota remains unsaturated, providing a critical window for modulation and influencing the subsequent microbiota succession, which may have long-term health outcomes. Microbiota transplantation (MT) involves transferring the microbiota from a donor to a recipient to modulate the recipient’s microbiota toward a desired state. Successfully applied in human medicine, MT is also gaining attention in poultry production to modulate intestinal health. This review comprehensively explores factors affecting MT, its mechanisms, and its potential applications in chickens, providing insights for further research and commercial use.
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institution Kabale University
issn 2049-1891
language English
publishDate 2025-06-01
publisher BMC
record_format Article
series Journal of Animal Science and Biotechnology
spelling doaj-art-3ffa71693bb54f679747a9fc898f49732025-08-20T03:31:41ZengBMCJournal of Animal Science and Biotechnology2049-18912025-06-0116112310.1186/s40104-025-01233-6Recent advances in the application of microbiota transplantation in chickensHaoran Zhao0Luke Comer1Muhammad Zeeshan Akram2Matthias Corion3Yang Li4Nadia Everaert5Nutrition and Animal-Microbiota Ecosystems Laboratory, Department of Biosystems, KU LeuvenNutrition and Animal-Microbiota Ecosystems Laboratory, Department of Biosystems, KU LeuvenNutrition and Animal-Microbiota Ecosystems Laboratory, Department of Biosystems, KU LeuvenNutrition and Animal-Microbiota Ecosystems Laboratory, Department of Biosystems, KU LeuvenNutrition and Animal-Microbiota Ecosystems Laboratory, Department of Biosystems, KU LeuvenNutrition and Animal-Microbiota Ecosystems Laboratory, Department of Biosystems, KU LeuvenAbstract Extensive evidence demonstrates that a healthy and well-balanced gut microbiota profoundly influences host nutrient absorption, immunity, and metabolism. Unlike mammals, early microbiota colonization in commercial poultry largely depends on the environment as chicks hatch in incubators under a relatively sterile environment (egg and incubator sterilization) without maternal-offspring interaction. The early gut microbiota remains unsaturated, providing a critical window for modulation and influencing the subsequent microbiota succession, which may have long-term health outcomes. Microbiota transplantation (MT) involves transferring the microbiota from a donor to a recipient to modulate the recipient’s microbiota toward a desired state. Successfully applied in human medicine, MT is also gaining attention in poultry production to modulate intestinal health. This review comprehensively explores factors affecting MT, its mechanisms, and its potential applications in chickens, providing insights for further research and commercial use.https://doi.org/10.1186/s40104-025-01233-6BehaviorGut healthImmunityMetabolismMicrobiota colonizationMicrobiota composition
spellingShingle Haoran Zhao
Luke Comer
Muhammad Zeeshan Akram
Matthias Corion
Yang Li
Nadia Everaert
Recent advances in the application of microbiota transplantation in chickens
Journal of Animal Science and Biotechnology
Behavior
Gut health
Immunity
Metabolism
Microbiota colonization
Microbiota composition
title Recent advances in the application of microbiota transplantation in chickens
title_full Recent advances in the application of microbiota transplantation in chickens
title_fullStr Recent advances in the application of microbiota transplantation in chickens
title_full_unstemmed Recent advances in the application of microbiota transplantation in chickens
title_short Recent advances in the application of microbiota transplantation in chickens
title_sort recent advances in the application of microbiota transplantation in chickens
topic Behavior
Gut health
Immunity
Metabolism
Microbiota colonization
Microbiota composition
url https://doi.org/10.1186/s40104-025-01233-6
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