Cargo-selective regulation of clathrin-mediated endocytosis by AMP-activated protein kinase

Summary: The cell surface abundance of many proteins is controlled by clathrin-mediated endocytosis (CME). CME is driven by the assembly of clathrin and other proteins on the inner leaflet of the plasma membrane into clathrin-coated pits (CCPs). Regulation of CCP dynamics allows for control of the f...

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Main Authors: Laura A. Orofiamma, Ralph Christian Delos Santos, Ayshin Mehrabi, Nikol Leshchyshyn, Geoffrey G. Hesketh, Sadia Rahmani, Aesha Patel, Farnaz Fekri, Rehman Ata, Colin D.H. Ratcliffe, Mathieu J.F. Crupi, Lois Mulligan, Morag Park, Anne-Claude Gingras, Costin N. Antonescu
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225013926
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