Knowledge mapping of autophagy in chronic obstructive pulmonary disease from 2004 to 2024: a bibliometric analysis

BackgroundChronic obstructive pulmonary disease (COPD) has become a major global healthcare issue due to its high prevalence and mortality rates. Increasing evidence suggests that autophagy plays a role in the development of COPD, yet there is a lack of bibliometric analyses on literature related to...

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Main Authors: Yating Zhang, Anqi Li, Sumei Xu, Haoge Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1514686/full
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author Yating Zhang
Anqi Li
Sumei Xu
Haoge Liu
author_facet Yating Zhang
Anqi Li
Sumei Xu
Haoge Liu
author_sort Yating Zhang
collection DOAJ
description BackgroundChronic obstructive pulmonary disease (COPD) has become a major global healthcare issue due to its high prevalence and mortality rates. Increasing evidence suggests that autophagy plays a role in the development of COPD, yet there is a lack of bibliometric analyses on literature related to autophagy and COPD. Therefore, this study aims to summarize the current research status, research direction, and research hotspots in the literature related to COPD and autophagy.MethodsA search was conducted on the Web of Science Core Collection for literature related to COPD and autophagy from October 2004 to October 2024. Subsequently, bibliometric and visualization analyses were performed on the included publications using R software, CiteSpace, and VOSviewer.ResultsA total of 481 published articles across 229 journals related to COPD and autophagy were included. During the study period, there was a trend of continuous growth in both the annual number of publications and citations in this field. The United States had the highest centrality, while China was the most productive country. Major research institutions included Maastricht University, Harvard University, and Jikei University. The American Journal of Physiology-Lung Cellular and Molecular Physiology, International Journal of Chronic Obstructive Pulmonary Disease, and Autophagy are the most influential journals in this field. The author with the most published papers is Araya J, while Choi AMK is the most influential author. Frequently appearing keywords include “oxidative stress,” “obstructive pulmonary disease,” “aging,” “apoptosis,” and “mitophagy.”ConclusionThis bibliometric study helps researchers quickly understand the research overview of autophagy and COPD, thus providing new insights and directions for future research in this field.
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spelling doaj-art-3ff223e28c7749efa26769d638cda22d2025-08-20T02:45:03ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-02-011210.3389/fmed.2025.15146861514686Knowledge mapping of autophagy in chronic obstructive pulmonary disease from 2004 to 2024: a bibliometric analysisYating Zhang0Anqi Li1Sumei Xu2Haoge Liu3Qinggang Town Health Center, Yuhuan Second People's Hospital Health Community Group Qinggang Branch, Taizhou, ChinaGuang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, ChinaThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, ChinaBackgroundChronic obstructive pulmonary disease (COPD) has become a major global healthcare issue due to its high prevalence and mortality rates. Increasing evidence suggests that autophagy plays a role in the development of COPD, yet there is a lack of bibliometric analyses on literature related to autophagy and COPD. Therefore, this study aims to summarize the current research status, research direction, and research hotspots in the literature related to COPD and autophagy.MethodsA search was conducted on the Web of Science Core Collection for literature related to COPD and autophagy from October 2004 to October 2024. Subsequently, bibliometric and visualization analyses were performed on the included publications using R software, CiteSpace, and VOSviewer.ResultsA total of 481 published articles across 229 journals related to COPD and autophagy were included. During the study period, there was a trend of continuous growth in both the annual number of publications and citations in this field. The United States had the highest centrality, while China was the most productive country. Major research institutions included Maastricht University, Harvard University, and Jikei University. The American Journal of Physiology-Lung Cellular and Molecular Physiology, International Journal of Chronic Obstructive Pulmonary Disease, and Autophagy are the most influential journals in this field. The author with the most published papers is Araya J, while Choi AMK is the most influential author. Frequently appearing keywords include “oxidative stress,” “obstructive pulmonary disease,” “aging,” “apoptosis,” and “mitophagy.”ConclusionThis bibliometric study helps researchers quickly understand the research overview of autophagy and COPD, thus providing new insights and directions for future research in this field.https://www.frontiersin.org/articles/10.3389/fmed.2025.1514686/fullautophagychronic obstructive pulmonary disease (COPD)bibliometric analysisCiteSpaceVOSviewer
spellingShingle Yating Zhang
Anqi Li
Sumei Xu
Haoge Liu
Knowledge mapping of autophagy in chronic obstructive pulmonary disease from 2004 to 2024: a bibliometric analysis
Frontiers in Medicine
autophagy
chronic obstructive pulmonary disease (COPD)
bibliometric analysis
CiteSpace
VOSviewer
title Knowledge mapping of autophagy in chronic obstructive pulmonary disease from 2004 to 2024: a bibliometric analysis
title_full Knowledge mapping of autophagy in chronic obstructive pulmonary disease from 2004 to 2024: a bibliometric analysis
title_fullStr Knowledge mapping of autophagy in chronic obstructive pulmonary disease from 2004 to 2024: a bibliometric analysis
title_full_unstemmed Knowledge mapping of autophagy in chronic obstructive pulmonary disease from 2004 to 2024: a bibliometric analysis
title_short Knowledge mapping of autophagy in chronic obstructive pulmonary disease from 2004 to 2024: a bibliometric analysis
title_sort knowledge mapping of autophagy in chronic obstructive pulmonary disease from 2004 to 2024 a bibliometric analysis
topic autophagy
chronic obstructive pulmonary disease (COPD)
bibliometric analysis
CiteSpace
VOSviewer
url https://www.frontiersin.org/articles/10.3389/fmed.2025.1514686/full
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