Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations.

After mitosis, mammalian chromosomes partially decondense to occupy distinct territories in the cell nucleus. Current models propose that territories are separated by an interchromatin domain, rich in soluble nuclear machinery, where only rare interchromosomal interactions can occur via extended chr...

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Bibliographic Details
Main Authors: Miguel R Branco, Ana Pombo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-05-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.0040138&type=printable
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