Candida Esophagitis in a Male Homosexual with Defective Neutrophil Function. A 'Pseudo-AIDS' Syndrome
36-year-old male homosexual presented with a prolonged history of odynophagia. Esophageal candidiasis was suspected at endoscopy and confirmed by biopsy ane cultures. Investigations demonstrated no evidence for underlying human immunodeficiency virus (HIV) infection hy either ELISA assay or Wes1ern...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1987-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1987/954647 |
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| _version_ | 1849304854062694400 |
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| author | Michael A Noble J Scott Whittaker Anil K Mangal Cedric J Carter Hugh J Freeman |
| author_facet | Michael A Noble J Scott Whittaker Anil K Mangal Cedric J Carter Hugh J Freeman |
| author_sort | Michael A Noble |
| collection | DOAJ |
| description | 36-year-old male homosexual presented with a prolonged history of
odynophagia. Esophageal candidiasis was suspected at endoscopy and confirmed by
biopsy ane cultures. Investigations demonstrated no evidence for underlying human
immunodeficiency virus (HIV) infection hy either ELISA assay or Wes1ern Blot technique,
and lymphocyte helper: supressor ratios were normal. A specific serum-dependent
factor that inhibited the candidacidal capability of his neutrophils, as well as those of
volunteer controls, was detected. This inhibitor disappeared after treatment of the
candidal infection. Severe and extensive esophagitis is not always indicative of an
underlying infection with HIV in homosexual mnles. Clinical criteria alone should not
be used to establish the diagnosis of AIDS, even in patients from recognized high
risk categories. |
| format | Article |
| id | doaj-art-3fd8bb9c82f54e04a0948ced4ff9404e |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 1987-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-3fd8bb9c82f54e04a0948ced4ff9404e2025-08-20T03:55:36ZengWileyCanadian Journal of Gastroenterology0835-79001987-01-0111333510.1155/1987/954647Candida Esophagitis in a Male Homosexual with Defective Neutrophil Function. A 'Pseudo-AIDS' SyndromeMichael A NobleJ Scott WhittakerAnil K MangalCedric J CarterHugh J Freeman36-year-old male homosexual presented with a prolonged history of odynophagia. Esophageal candidiasis was suspected at endoscopy and confirmed by biopsy ane cultures. Investigations demonstrated no evidence for underlying human immunodeficiency virus (HIV) infection hy either ELISA assay or Wes1ern Blot technique, and lymphocyte helper: supressor ratios were normal. A specific serum-dependent factor that inhibited the candidacidal capability of his neutrophils, as well as those of volunteer controls, was detected. This inhibitor disappeared after treatment of the candidal infection. Severe and extensive esophagitis is not always indicative of an underlying infection with HIV in homosexual mnles. Clinical criteria alone should not be used to establish the diagnosis of AIDS, even in patients from recognized high risk categories.http://dx.doi.org/10.1155/1987/954647 |
| spellingShingle | Michael A Noble J Scott Whittaker Anil K Mangal Cedric J Carter Hugh J Freeman Candida Esophagitis in a Male Homosexual with Defective Neutrophil Function. A 'Pseudo-AIDS' Syndrome Canadian Journal of Gastroenterology |
| title | Candida Esophagitis in a Male Homosexual with Defective Neutrophil Function. A 'Pseudo-AIDS' Syndrome |
| title_full | Candida Esophagitis in a Male Homosexual with Defective Neutrophil Function. A 'Pseudo-AIDS' Syndrome |
| title_fullStr | Candida Esophagitis in a Male Homosexual with Defective Neutrophil Function. A 'Pseudo-AIDS' Syndrome |
| title_full_unstemmed | Candida Esophagitis in a Male Homosexual with Defective Neutrophil Function. A 'Pseudo-AIDS' Syndrome |
| title_short | Candida Esophagitis in a Male Homosexual with Defective Neutrophil Function. A 'Pseudo-AIDS' Syndrome |
| title_sort | candida esophagitis in a male homosexual with defective neutrophil function a pseudo aids syndrome |
| url | http://dx.doi.org/10.1155/1987/954647 |
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