Candida Esophagitis in a Male Homosexual with Defective Neutrophil Function. A 'Pseudo-AIDS' Syndrome
36-year-old male homosexual presented with a prolonged history of odynophagia. Esophageal candidiasis was suspected at endoscopy and confirmed by biopsy ane cultures. Investigations demonstrated no evidence for underlying human immunodeficiency virus (HIV) infection hy either ELISA assay or Wes1ern...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1987-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1987/954647 |
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| Summary: | 36-year-old male homosexual presented with a prolonged history of
odynophagia. Esophageal candidiasis was suspected at endoscopy and confirmed by
biopsy ane cultures. Investigations demonstrated no evidence for underlying human
immunodeficiency virus (HIV) infection hy either ELISA assay or Wes1ern Blot technique,
and lymphocyte helper: supressor ratios were normal. A specific serum-dependent
factor that inhibited the candidacidal capability of his neutrophils, as well as those of
volunteer controls, was detected. This inhibitor disappeared after treatment of the
candidal infection. Severe and extensive esophagitis is not always indicative of an
underlying infection with HIV in homosexual mnles. Clinical criteria alone should not
be used to establish the diagnosis of AIDS, even in patients from recognized high
risk categories. |
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| ISSN: | 0835-7900 |