Evaluation of Immunogenicity of <i>Mycobacterium tuberculosis ag85ab</i> DNA Vaccine Delivered by Pulmonary Administration

Evaluation of Immunogenicity of <i>Mycobacterium tuberculosis ag85ab</i> DNA Vaccine Delivered by Pulmonary Administration

<b>Background:</b> Tuberculosis (TB) is a respiratory infectious disease, and the current TB vaccine has low local lung protection. We aim to optimize immune pathways to improve the immunogenicity of vaccines. <b>Methods:</b> In the immunogenicity study, 50 BALB/c mice were r...

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Bibliographic Details
Main Authors: Haimei Zhao, Zhen Zhang, Yong Xue, Nan Wang, Yinping Liu, Xihui Ma, Lan Wang, Xiaoou Wang, Danyang Zhang, Junxian Zhang, Xueqiong Wu, Yan Liang
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Vaccines
Subjects:
<i>Mycobacterium tuberculosis</i>
DNA vaccine
pulmonary delivery
electroporation
immunogenicity
Online Access:https://www.mdpi.com/2076-393X/13/5/442
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