Solitary Encapsulated Neurofibroma Not Associated with Neurofibromatosis-1 Affecting Tongue in a 73-Year-Old Female

Neurofibromas are benign tumors of nerve cell origin arising due to proliferation of Schwann cells and fibroblasts. They are usually asymptomatic and hence remain undiagnosed. They are commonly found on the skin and intraorally tongue is the most common site for their occurrence. Here, we present a...

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Main Authors: Sk. Abdul Mahmud, Neha Shah, Moumita Chattaraj, Swagata Gayen
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2016/3630153
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author Sk. Abdul Mahmud
Neha Shah
Moumita Chattaraj
Swagata Gayen
author_facet Sk. Abdul Mahmud
Neha Shah
Moumita Chattaraj
Swagata Gayen
author_sort Sk. Abdul Mahmud
collection DOAJ
description Neurofibromas are benign tumors of nerve cell origin arising due to proliferation of Schwann cells and fibroblasts. They are usually asymptomatic and hence remain undiagnosed. They are commonly found on the skin and intraorally tongue is the most common site for their occurrence. Here, we present a unique case of solitary encapsulated neurofibroma in the oral cavity without any clinical manifestations or family history of Neurofibromatosis type 1 in a 73-year-old female patient who presented with a painless swelling on the tongue. The histopathologic findings closely mimicked benign fibrous histiocytoma. In our case, definitive diagnosis of neurofibroma was made based on clinical findings, family history, and histopathological and immunohistochemical evaluation. Through this case report we want to emphasize the role of biopsy and immunohistochemistry in arriving at a confirmatory diagnosis. The patient was treated by surgical excision and showed no signs of recurrence over a follow-up period of 12 months.
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issn 2090-6447
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publishDate 2016-01-01
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series Case Reports in Dentistry
spelling doaj-art-3fca9cdd2a504e19a75163463fde1c352025-02-03T06:45:17ZengWileyCase Reports in Dentistry2090-64472090-64552016-01-01201610.1155/2016/36301533630153Solitary Encapsulated Neurofibroma Not Associated with Neurofibromatosis-1 Affecting Tongue in a 73-Year-Old FemaleSk. Abdul Mahmud0Neha Shah1Moumita Chattaraj2Swagata Gayen3Department of Oral & Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences & Research, 157/F Nilgunj Road, Panihati, Kolkata 700114, IndiaDepartment of Oral & Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences & Research, 157/F Nilgunj Road, Panihati, Kolkata 700114, IndiaDepartment of Oral & Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences & Research, 157/F Nilgunj Road, Panihati, Kolkata 700114, IndiaDepartment of Oral & Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences & Research, 157/F Nilgunj Road, Panihati, Kolkata 700114, IndiaNeurofibromas are benign tumors of nerve cell origin arising due to proliferation of Schwann cells and fibroblasts. They are usually asymptomatic and hence remain undiagnosed. They are commonly found on the skin and intraorally tongue is the most common site for their occurrence. Here, we present a unique case of solitary encapsulated neurofibroma in the oral cavity without any clinical manifestations or family history of Neurofibromatosis type 1 in a 73-year-old female patient who presented with a painless swelling on the tongue. The histopathologic findings closely mimicked benign fibrous histiocytoma. In our case, definitive diagnosis of neurofibroma was made based on clinical findings, family history, and histopathological and immunohistochemical evaluation. Through this case report we want to emphasize the role of biopsy and immunohistochemistry in arriving at a confirmatory diagnosis. The patient was treated by surgical excision and showed no signs of recurrence over a follow-up period of 12 months.http://dx.doi.org/10.1155/2016/3630153
spellingShingle Sk. Abdul Mahmud
Neha Shah
Moumita Chattaraj
Swagata Gayen
Solitary Encapsulated Neurofibroma Not Associated with Neurofibromatosis-1 Affecting Tongue in a 73-Year-Old Female
Case Reports in Dentistry
title Solitary Encapsulated Neurofibroma Not Associated with Neurofibromatosis-1 Affecting Tongue in a 73-Year-Old Female
title_full Solitary Encapsulated Neurofibroma Not Associated with Neurofibromatosis-1 Affecting Tongue in a 73-Year-Old Female
title_fullStr Solitary Encapsulated Neurofibroma Not Associated with Neurofibromatosis-1 Affecting Tongue in a 73-Year-Old Female
title_full_unstemmed Solitary Encapsulated Neurofibroma Not Associated with Neurofibromatosis-1 Affecting Tongue in a 73-Year-Old Female
title_short Solitary Encapsulated Neurofibroma Not Associated with Neurofibromatosis-1 Affecting Tongue in a 73-Year-Old Female
title_sort solitary encapsulated neurofibroma not associated with neurofibromatosis 1 affecting tongue in a 73 year old female
url http://dx.doi.org/10.1155/2016/3630153
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AT moumitachattaraj solitaryencapsulatedneurofibromanotassociatedwithneurofibromatosis1affectingtongueina73yearoldfemale
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